摘要【目的】探讨绝经及未绝经女性子宫动态增强1.5 T磁共振成像(MRI)检查结果差异。【方法】选取2017年1月至2019年1月榆林市星元医院收治的83例拟行盆腔动态增强MRI检查的绝经患者为观察组,另选取同期入院体检的83例未绝经女性作为对照组。比较两组子宫基本参数(子宫结合带厚度、宽径、长径、高径、内膜厚度及子宫外肌层厚度)、动态增强MRI定量参数值(容积转运常数、速率转运常数、容积分数)及子宫肌层T2加权像(T2WI)信号强度。【结果】两组子宫结合带厚度比较,差异无统计学意义(P>0.05);观察组子宫宽径、长径、高径均显著短于对照组(P<0.05),子宫外肌层厚度、子宫内膜厚度显著厚于对照组(P<0.05)。两组子宫肌层中间T2WI信号强度、子宫结合带处容积转运常数和速率转运常数、子宫内膜处容积分数比较,差异无统计学意义(P>0.05);观察组子宫肌层内侧、外侧T2WI信号强度显著低于对照组(P>0.05),子宫结合带处容积分数显著低于对照组(P<0.05),子宫肌层处容积转运常数、速率转运常数、容积分数显著低于对照组(P<0.05),子宫内膜处容积转运常数、速率转运常数显著低于对照组(P<0.05)。【结论】采用动态增强1.5 T MRI可清晰观察到绝经及未绝经女性子宫形态、结构的差异,如绝经后子宫萎缩及子宫内膜和肌层增厚等,对临床医生认识绝经前后子宫变化有重要指导作用。
Abstract：【Objective】 To analyze the difference of uterine dynamic contrast-enhanced 1.5 T magnetic resonance imaging (MRI) results between postmenopausal and premenopausal women. 【Methods】 A total of 83 postmenopausal patients scheduled for pelvic dynamic contrast-enhanced MRI in Xingyuan Hospital of Yulin City from January 2017 to January 2019 were selected as the observation group,while 83 premenopausal women who were admitted for physical examination at the same time were selected as the control group. The basic parameters of uterus (junction zone thickness,width diameter,length diameter,height diameter,myometrium thickness,endometrial thickness),dynamic contrast-enhanced MRI quantitative parameters (volume transport constant,rate transport constant,volume fraction) and signal intensity of uterine myometrium T2 weighted image (T2WI) were recorded. 【Results】 There was no significant difference in the thickness of uterine junction zone between the two groups (P>0.05),while the width diameter,length diameter and height diameter of uterus in the observation group were significantly lower than those in the control group (P<0.05),and the thickness of extrauterine muscle layer and endometrial layer were significantly higher than those of the control group (P<0.05).There were no significant differences in terms of the signal intensity of T2WI in the middle part of myometrium,volume transport constant and rate transport constant at the junction of uterus,and endometrial volume fraction between the two groups (P>0.05). The signal intensity of T2WI in the medial and lateral parts of myometrium in the observation group was significantly lower than that in the control group (P>0.05) and the volume fraction of myometrium in the observation group was significantly lower than that in the control group (P<0.05). The volume transport constant,rate transport constant and volume fraction in the endometrium were significantly lower than those in the control group (P<0.05). 【Conclusion】 Dynamic contrast-enhanced 1.5 T MRI can clearly observe the differences of uterine morphology and structure between postmenopausal and premenopausal women,such as postmenopausal uterine atrophy,endometrial thickening,myometrium thickening,which may provide helpful info for clinicians.
张学平, 常娟锋. 绝经及未绝经女性子宫动态增强1.5 T MRI检查结果比较[J]. 医学临床研究, 2023, 40(3): 407-410.
ZHANG Xue-ping, CHANG Juan-feng. Analysis of the Difference of Uterine Dynamic Contrast-enhanced 1.5 T MRI between Postmenopausal and Premenopausal Women. JOURNAL OF CLINICAL RESEARCH, 2023, 40(3): 407-410.
2023, Vol. 40 
