Abstract：【Objective】To investigate the relationship between the middle cerebral artery (MCA) atherosclerotic plaque and its correlation with acute cerebral infarction (ACI). 【Methods】A total of 56 patients with symptomatic middle cerebral artery stenosis were collected and divided into acute cerebral infarction group(ACI group) and non-acute cerebral infarction(NACI group) according to diffusion weighted imaging (DWI). First,Univariate analysis was used to analyze the differences in the differences the lumen stenosis rate,plaque location,shape,length and enhancement degree between the two groups of patients. Binary logistic regression and receiver operating characteristic (ROC) curve were constructed to evaluate the efficacy of selected variables in predicting cerebral infarction. 【Results】The plaque length and the proportion of plaque enhancement in the ACI group were higher than those in the NACI group,the difference was statistically significant (P<0.05). Multivariate logistic regression analysis showed that plaque length and plaque enhancement were independent risk factors for ACI in patients with symptomatic MCA stenosis (P<0.05). The AUC of lumen stenosis rate,plaque length,plaque enhancement and their combination to predict the occurrence of ACI were 0.611,0.836,0.782 and 0.877,respectively. The predictive efficacy of plaque length and plaque enhancement degree on cerebral infarction was higher than lumen stenosis rate (P<0.05),and the combination of the three could significantly improve the predictive efficacy of cerebral infarction (P<0.05). 【Conclusion】The length and intensity of plaque are independent risk factors for ACI in patients with symptomatic MCA stenosis. Both of them are superior to lumen stenosis in predicting the occurrence of acute cerebral infarction. The combined detection of the three can improve the diagnostic efficacy of ACI.
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2023, Vol. 40 
