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医学临床研究  2022, Vol. 39 Issue (12): 1771-1774    DOI: 10.3969/j.issn.1671-7171.2022.12.004
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盐酸哌甲酯控释片联合电子生物反馈治疗儿童注意缺陷多动障碍的疗效
裴军强1, 张瑜2**
1.陕西省咸阳市中心医院120急救中心,陕西 咸阳 712100;
2.榆林市第二医院儿科,陕西 榆林 714000
Study on Effects of Methylphenidate Hydrochloride-controlled Release Tablets Combined with Electronic Biofeedback on Efficacy of Children with ADHD
PEI Jun-qiang, ZHANG Yu
120 Emergency Center, Xianyang Central Hospital,Xianyang Shaanxi 712100
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摘要 【目的】探讨盐酸哌甲酯控释片联合电子生物反馈治疗儿童注意缺陷多动障碍(ADHD)的疗效。【方法】两院门诊就诊的80例ADHD患儿,随机分为观察组和对照组,每组40例。对照组采用盐酸哌甲酯控释片治疗,观察组采用盐酸哌甲酯控释片联合电子生物反馈治疗,治疗疗程均为2个月。比较两组患者疗效及不良反应发生情况和治疗前后各项相关评分情况。【结果】观察组总有效率明显高于对照组,且差异有统计学意义(P<0.05)。治疗结束及治疗结束1个月后,两组Cornner因子评分较治疗前均有所降低,其中观察组学习因子、焦虑因子、行为因子、多动因子和身心因子明显低于对照组,且差异有统计学意义(P<0.05)。治疗后及治疗结束1个月,两组发声抽动、运动抽动评分与治疗前评分比较均降低(P<0.05),且观察组较对照组评分下降更明显(P<0.05);两组患儿治疗后及治疗结束后1个月各项认知功能项目评分均高于治疗前,且观察组治疗后各时段认知功能评分明显高于对照组(P<0.05)。【结论】盐酸哌甲酯联合电子生物反馈治疗能有效治疗ADHD,改善患儿认知功能、抽动障碍,显著提高临床疗效。
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裴军强
张瑜
关键词 注意力缺陷障碍伴多动哌醋甲酯/药理学神经反馈治疗结果    
Abstract:【Objective】To explore effects of methylphenidate hydrochloride-controlled release tablets combined with electronic biofeedback on the clinical efficacy of children with attention deficit hyperactivity disorder (ADHD). 【Methods】A total of 80 children with ADHD were randomly divided into the observation group and the control group (with 40 cases in each group). The control group was treated with methylphenidate hydrochloride controlled-release tablets,while the observation group was treated with methylphenidate hydrochloride controlled-release tablets combined with electronic biofeedback. The course of treatment in both groups was 2 months. The therapeutic effect of the two groups before and after treatment,the adverse reactions and scores were observed and analyzed. 【Results】The total effective rate in the observation group was significantly higher than that in the control group,and the difference was statistically significant (P<0.05). After treatment and one month after the end of treatment,the scores of Conner factors in the two groups decreased if compared to the scores before treatment (P<0.05); And the scores in the observation group decreased even more significantly than those in the control group after treatment (P<0.05). The scores of various cognitive function items such as the learning factor,anxiety factor,behavior factor,hyperactivity factor and physical and mental factor in the two groups after treatment and 1 month after treatment were higher than those before treatment.The scores of vocal tics and motor tics in the two groups after treatment and 1 month after the end of treatment were all lower than those before treatment (P<0.05),and the scores in the observation group were significantly lower than those in the control group (P<0.05). The cognitive function scores in the observation group were significantly higher than those in the control group at each time points after treatment (P<0.05). 【Conclusion】The combination of methylphenidate hydrochloride and electronic biofeedback can effectively treat ADHD,improve children's cognitive function and tic disorder,and significantly improve the clinical effect.
Key wordsAttention Deficit Disorder with Hyperactivity    Methylphenidate/PD    Neurofeedback    Treatment Outcome
收稿日期: 2022-01-20     
中图分类号:  R725  
基金资助:* 陕西省卫生健康科研基金项目(编号:2021E005)
通讯作者: **E-mail:2396021957@qq.com   
引用本文:   
裴军强, 张瑜. 盐酸哌甲酯控释片联合电子生物反馈治疗儿童注意缺陷多动障碍的疗效[J]. 医学临床研究, 2022, 39(12): 1771-1774.
PEI Jun-qiang, ZHANG Yu. Study on Effects of Methylphenidate Hydrochloride-controlled Release Tablets Combined with Electronic Biofeedback on Efficacy of Children with ADHD. JOURNAL OF CLINICAL RESEARCH, 2022, 39(12): 1771-1774.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2022.12.004     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2022/V39/I12/1771
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