Clinical Efficacy of Supportive Expressive Group Psychological Intervention Combined with Paliperidone Palmitate in the Treatment of Acute First-Episode Schizophrenia
Abstract：【Objective】 To explore the clinical effect of supportive expressive group psychological intervention combined with paliperidone palmitate in the treatment of acute first-episode schizophrenia. 【Methods】 The clinical data of 98 patients with acute first-episode schizophrenia treated in our hospital from January 2019 to February 2021 were analyzed retrospectively. According to different treatment methods, they were divided into observation group and control group, with 49 cases in each group. The control group was treated with paliperidone palmitate sustained-release tablets, and the observation group was given supportive expressive group psychological intervention on the basis of the control group. The scores of positive and negative emotional state scale (PANAS), social function deficiency screening scale (SDSS) and quality of life scale for patients with schizophrenia (SQLS) were compared between the two groups before and after treatment. 【Results】 After one month and three months of treatment, the positive emotion score of the two groups was higher than that before treatment, and the negative emotion score was lower than that before treatment. There was significant difference between the two groups after three months of treatment and one month of treatment, as well as between the two groups (all P<0.05); The social function defect score of the two groups was lower than that before treatment, and there was significant difference between the two groups after 3 months of treatment and 1 month of treatment, as well as between the two groups (all P<0.05); The scores of motivation and energy, psychosocial, symptoms and side effects of the two groups were lower than those before treatment, and there were significant differences between the two groups after 3 months of treatment and 1 month of treatment, as well as between the two groups (all P<0.05). 【Conclusion】 Supportive expressive group psychological intervention combined with paliperidone palmitate can better improve the emotional state, restore the social function and improve the quality of life of patients with acute first-episode schizophrenia.
赵文青. 支持性-表达性团体心理干预联合棕榈酸帕利哌酮治疗急性期首发精神分裂症患者的临床疗效[J]. 医学临床研究, 2022, 39(5): 690-692.
ZHAO Wen-qing. Clinical Efficacy of Supportive Expressive Group Psychological Intervention Combined with Paliperidone Palmitate in the Treatment of Acute First-Episode Schizophrenia. JOURNAL OF CLINICAL RESEARCH, 2022, 39(5): 690-692.
2022, Vol. 39 
