Abstract：【Objective】To explore the changes and clinical value of thromboelastography in acute cerebrovascular disease patients. 【Methods】A total of 146 patients with acute cerebrovascular disease (73 patients with acute cerebral hemorrhage and 73 patients with acute cerebral infarction) treated in our hospital were collected in this study. All of them received CT scanning after admission to evaluate the volume of cerebral hemorrhage and area of cerebral infarction. Venous bloods were collected to detect level of TEG [coagulation reaction time (R), blood formation time (K), angle, maximum amplitude (MA) and coagulation index (CI)] to compare the difference between two groups and analyze the relationship of TEG indexes with the amount of cerebral hemorrhage and area of cerebral infarction. Meanwhile, the value of TEG to distinguish the two types of acute cerebrovascular disease was identified by using receiver operating characteristic (ROC) curve. 【Results】 (1) the K time and R time of the cerebral hemorrhage group were higher than those of the cerebral infarction group, while angle and CI levels were lower than those in the cerebral infarction group (P<0.01). (2) Compared to cerebral hemorrhage 30 mL, patients with cerebral hemorrhage 30 mL had shorter K time, while they had higher value of MA and angle; Compared to patients with small and medium-sized cerebral infarction, patients with large-area cerebral infarction had lower R time and higher value of MA and angle (P<0.01). (3) The ROC curve found that the value of K-time, R-time, angle and CI for diagnosis of cerebral hemorrhage were 0.73(0.64-0.81), 0.82(0.75-0.89), 0.76(0.68-0.84) and 0.65 (0.60-0.74),respectively; and all p values were less than 0.05. 【Conclusion】The level of TEG in acute cerebral hemorrhage and acute cerebral infarction was significantly different. It can be used as an index to identify acute cerebral hemorrhage and infarction, which had a relationship with the status of acute cerebrovascular disease.
2021, Vol. 38 
