Abstract：【Objective】 To explore the application and evaluation of Westgard sigma rule in the quality control of homocysteine (HCY). 【Methods】 The quality control values of HCY detection from January 2018 to June 2018 (before the use of the Westgard Sigma rule) and July 2018 to December 2018 (after the use of the Westgard Sigma rule) were selected to analyze the out-of-control rate, CV, Bias and the σ values of the two quality control methods. 【Results】 The total out-of-control rate of HCY detection was 2.21% before using Westgard Sigma rule and 1.27% after using HCY rule. The average Bias and CV of Westgard Sigma rule using HCY indoor quality assessment were 2.50% and 7.17%, respectively, and the average Bias and CV after using HCY were 1.82% and 5.66%, respectively. The σ values of low, medium and high HCY indoor quality evaluation before using the Westgard Sigma rule were 7.32, 7.89 and 8.17, which were all greater than 6. The σ values of low, medium and high HCY indoor quality evaluation after using were 5.53, 5.85 and 6.04, that is, the σ values after using the Westgard Sigma rule were lower than before using. 【Conclusion】 Westgard Sigma rule can be used for HCY indoor quality testing and quality improvement, and has clinical application value.
2021, Vol. 38 
