医学临床研究
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医学临床研究  2021, Vol. 38 Issue (1): 88-90    DOI: 10.3969/j.issn.1671-7171.2021.01.026
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地西泮联合缩宫素对产程潜伏期延长倾向产妇产程及妊娠结局的影响
王建英, 王新丽
德州市妇女儿童医院妇产科,山东 德州 253017
Effect of Diazepam Combined with Oxytocin on Labor Process and Pregnancy Outcome of Pregnant Women with Prolonged Latent Labor Duration
WANG Jian-ying, WANG Xin-li
Department of Obstetrics,Dezhou Maternal and Child Health Hospital, Dezhou,Shandong 253017
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摘要 【目的】探讨地西泮联合缩宫素对产程潜伏期延长倾向产妇产程及妊娠结局的影响。【方法】回顾性分析2017年3月至2018年3月在本院分娩的300例有产程潜伏期延长倾向的产妇的临床资料。根据治疗方式的不同分为观察组和对照组,每组150例。观察组采用地西泮联合缩宫素治疗,对照组仅采用缩宫素治疗。比较两组产妇的宫颈和产程情况(宫口全开时间、宫口扩张速度、第一产程时间和第二产程时间)和妊娠结局(阴道分娩率、宫颈水肿率和裂伤率、胎儿窘迫发生率和产后2 h出血量)。并于分娩结束后24 h采用生活质量(QOL)评分评估两组产妇生活质量。【结果】观察组用药后宫口全开时间、第一产程和第二产程时间均显著短于对照组,宫口扩张速度大于对照组,差异有统计学意义(P<0.05)。观察组阴道分娩率显著高于对照组,宫颈水肿率、宫颈裂伤率、胎儿窘迫发生率和产后2 h出血量均低于对照组,差异有统计学意义(P<0.05)。产后12 h,观察组的QOL评分显著高于对照组,差异有统计学意义(P<0.05)。【结论】地西泮联合缩宫素应用于产程潜伏期延长倾向的产妇,可加速产程进展,改善妊娠结局,提高产妇生活质量,值得临床推广应用。
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王建英
王新丽
关键词 分娩分娩产道地西泮/治疗应用催产素/治疗应用妊娠结局    
Abstract:【Objective】To explore the effect of diazepam combined with oxytocin on labor process and pregnancy outcome of pregnant women with prolonged latency tendency. 【Methods】The clinical data of 300 cases of maternal diagnosis and treatment with a tendency to prolong the incubation period in our hospital from March 2017 to March 2018 were analyzed retrospectively. According to different treatment methods, patients were divided into two groups, 150 in each group. The observation group was treated with diazepam and oxytocin, and the control group was only treated with oxytocin. The cervix and labor status (total opening time of uterine orifice, dilatation rate, first stage of labor and second stage of labor), pregnancy outcome (vaginal delivery rate, cervical edema rate and laceration rate, incidence of fetal distress and postpartum 2h bleeding), and the Quality of Life (QOL) score at 24 hours postpartum were compared between the two groups. 【Results】The uterine ostium total opening time, the first stage of labor and the second stage of labor in the observation group were significantly shorter than those of the control group, and the dilatation rate of the uterine orifice was significantly faster than that of the control group (P<0.05). The vaginal delivery rate of the observation group was significantly higher than that of the control group, and the cervical edema rate, cervical laceration rate, the incidence of fetal distress and the amount of postpartum hemorrhage were lower than those of the control group (P<0.05). The QOL score of the observation group was statistically higher than that of the control group postpartum 24h(P<0.05). 【Conclusion】Diazepam combined with oxytocin can accelerate the progress of labor, improve pregnancy outcome, raise QOL score and improve the quality of life of women with prolonged latency tendency.
Key wordsParturition    Labor    Obstetric    Pregnancy Outcome    Diazepam/TU    Oxytocin/TU
收稿日期: 2018-10-08     
中图分类号:  R714.3  
引用本文:   
王建英, 王新丽. 地西泮联合缩宫素对产程潜伏期延长倾向产妇产程及妊娠结局的影响[J]. 医学临床研究, 2021, 38(1): 88-90.
WANG Jian-ying, WANG Xin-li. Effect of Diazepam Combined with Oxytocin on Labor Process and Pregnancy Outcome of Pregnant Women with Prolonged Latent Labor Duration. JOURNAL OF CLINICAL RESEARCH, 2021, 38(1): 88-90.
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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2021.01.026     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2021/V38/I1/88
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