Effect of THR through Anterior Minimally Invasive Approach on the Levels of HB, CRP, IL-6 and the Range of Hip Joint Motion Flexion and Extension in Patients with Femoral Neck Fracture
WANG Sheng-tao, YIN Yong, ZHANG Bo, et al
Department of Orthopedics, The 3rd Affiliated Hospital of Chengdu Medical College Pidu District People's Hospital, Chengdu Sichuan, 611700
Abstract：【Objective】To investigate the effect of total hip arthroplasty (THR) through anterior minimally invasive approach on the levels of hemoglobin (HB), C-reactive protein (CRP), interleukin-6 (IL-6) and the range of motion of hip joint flexion and extension in patients with femoral neck fracture. 【Methods】The clinical data of TRH patients (observation group,n=42) and traditional posterior approach thr patients (control group,n=42) were retrospectively analyzed from January 2017 to December 2019 in our hospital. The perioperative indexes (operation time, incision length, intraoperative blood loss, postoperative drainage, length of hospital stay), preoperative and postoperative blood indexes (Hb, Hct), inflammatory indexes (CRP, IL-6), hip flexion and extension range of motion and hip function score (Harris score) were compared between the two groups. 【Results】There were statistically significant differences in the perioperative indexes (except operation time) between the two groups (P<0.05); after 24 h, the levels of Hb and Hct in the two groups were significantly lower than those before operation (P<0.05), but the observation group was significantly higher than the control group (P<0.05); 24 h, 7 d after operation, the levels of Hb and Hct in the two groups were significantly lower than those before operation (P<0.05). The levels of CRP and IL-6 in the two groups were significantly higher than those before operation (P<0.05), but the observation group was significantly lower than the control group (P<0.05); after 3, 6, 12 months, the hip joint flexion and extension activity and Harris score of the two groups were significantly increased (P<0.05), the above indexes of the observation group were significantly higher than those of the control group at 3 months after operation (P<0.05), and the hip of the observation group at 6 and 12 months after operation was significantly higher than that of the control group (P<0.05) The range of motion of joint flexion and extension was significantly higher than that of the control group (P<0.05), but there was no significant difference in Harris score between the two groups (P>0.05). 【Conclusion】Anterior minimally invasive THR is more conducive to postoperative rehabilitation, shorten hospital stay, reduce inflammatory reaction, increase the range of motion of hip joint flexion and extension, shorten the recovery time of hip joint function, which is worthy of clinical application.
王胜涛, 殷勇,张波, 蔡杰勇, 肖波, 石波, 康斌. 前侧微创入路全髋关节置换术对股骨颈骨折患者Hb、CRP、IL-6水平及髋关节屈伸活动度的影响[J]. 医学临床研究, 2020, 37(12): 1840-1843.
WANG Sheng-tao, YIN Yong, ZHANG Bo, et al. Effect of THR through Anterior Minimally Invasive Approach on the Levels of HB, CRP, IL-6 and the Range of Hip Joint Motion Flexion and Extension in Patients with Femoral Neck Fracture. JOURNAL OF CLINICAL RESEARCH, 2020, 37(12): 1840-1843.
2020, Vol. 37 
