超声引导下神经阻滞对全膝关节置换患者术后VAS评分、血清疼痛介质的影响

doi:10.3969/j.issn.1671-7171.2020.10.007

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (0 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要 【目的】 探讨超声引导下神经阻滞对全膝关节置换(TKA)患者手术后视觉模拟疼痛评分(VAS)、血清疼痛介质5-羟色胺(5-HT)、β-内啡肽(β-EP)、白细胞介素-6(IL-6)、血浆P物质(SP)的影响。【方法】 本院实施下肢神经阻滞TKA手术的患者90例,随机分为两组,各45例,观察组术后采用超声引导下神经阻滞镇痛,对照组采用关节腔内注射镇痛药物镇痛。比较两组患者术后48 h内静息、活动时的VAS评分,对比术前、术后24 h两组患者血清5-HT、β-EP、SP、IL-6水平变化。【结果】 静息状态及活动状态下,观察组患者在术后6 h、12 h、24 h、48 h的VAS评分均低于对应时间点的对照组患者,且两组之间比较差异均有显著性(P<0.05)。术前两组患者的血清5-HT、β-EP、SP、IL-6水平差异无显著性(P>0.05);术后24 h,观察组患者的血清SP、IL-6水平低于,5-HT、β-EP水平显著高于对照组(P<0.05)。【结论】 超声引导下神经阻滞对TKA患者具有更好的镇痛效果,可调节患者疼痛相关因子的释放。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	刘金龙
	吕宝胜
	陈欢
	王佳璐

关键词 ：关节成形术, 置换, 膝, 神经传导阻滞/方法, 麻醉

Abstract：【Objective】 To investigate the effects of ultrasound-guided never block on postoperative visual analogue pain score (VAS), serum serotonin (5-HT), β-endorphin (β-EP), plasma substance P (SP) and interleukin 6 (IL-6) in patients undergoing total knee arthroplasty (TKA). 【Methods】 Ninety patients with lower extremity nerve block TKA in our hospital were randomly divided into two groups with 45 cases each. The experimental group was treated with ultrasound-guided nerve block analgesia and the control group was treated with intra-injection of analgesic drugs. The VAS scores of the patients at rest and activity within 48 hours after operation were compared between the two groups. The serum 5-HT, β-EP, SP, IL-6 were compared between the preoperative and postoperative 24h. 6 levels. 【Results】 No matter of resting and active states, the VAS scores of patients in the experimental group at 6h, 12h, 24h, 48h after operation were lower than those in the control group at the corresponding time points. The differences were statistically significant (P<0.05). Before operation, the serum of levels of EP, SP and IL-6 the two groups were no significant differences (P>0.05). The serum SP and IL-6 levels in the experimental group at 24h after surgery were lower, while the levels of 5-HT and β-EP were significantly higher than those in the control group (P<0.05). 【Conclusion】 Ultrasound-guided nerve block has better analgesic effects on TKA patients through regulating the release of pain-related factors in patients.

Key words： Arthroplasty Replacement Knee Nerve Block/MT Anesthesia

收稿日期: 2019-05-31

PACS:

R684.76

基金资助:河北省2016年度医学科学研究重点课题计划(No.20160323)

引用本文:

刘金龙, 吕宝胜, 陈欢, 王佳璐. 超声引导下神经阻滞对全膝关节置换患者术后VAS评分、血清疼痛介质的影响[J]. 医学临床研究, 2020, 37(10): 1465-1467.
LIU Jin-long, LV Bao-sheng, CHEN Huan, et al. Effect of Ultrasound-guided Nerve Block on Postoperative VAS Score and Serum Pain Mediator in Patients with Total Knee Arthroplastry. JOURNAL OF CLINICAL RESEARCH, 2020, 37(10): 1465-1467.

链接本文:

http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.10.007 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I10/1465