Abstract：【Objective】 To explore the effect of continuous lumbar plexus block on cognitive function in patients after knee replacement surgery. 【Methods】 We selected 82 patients with knee replacement surgery who were treated in our hospital were as subjects. All patients were randomly divided into two groups, with 41 cases in each group. Patients in the control group received intravenous analgesia, while patients in the observation group received continuous lumbar plexus block for the surgery.The postoperative recovery time, the VAS score, the incidence of adverse reactions, the changes of the simple mental state scale and cognitive dysfunction were compared between the two groups. 【Results】 The recovery time of the observation group, the VAS score at 12h and 24h after operation in the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions such as nausea and vomiting, dizziness, urinary retention in the observation group was 12.20%,which was lower than 31.71% in the control group (P<0.05).The MMSE score of the observation group was 24.73±3.16, and only 1 case (2.44%) of cognitive dysfunction occurred. However, the MMSE score of the control group was 20.38±2.91, and the cognitive dysfunction occurred in 5 cases (12.20%). The differences between the two groups were statistically significant. (P<0.05). 【Conclusion】 Continuous lumbar plexus block is more effective in patients undergoing knee replacement surgery, which can accelerate the postoperative recovery time of patients and has a positive effect on reducing pain, postoperative complications and cognitive dysfunction. It is worth promoting clinically.
刘寻, 杨智勇, 鄢庆林, 唐兰. 连续腰丛神经阻滞对膝关节置换手术后患者认知功能的影响[J]. 医学临床研究, 2020, 37(10): 1514-1516.
LIU Xun, YANG Zhi-yong, YAN Qing-lin, et al. Effect of Continuous Lumbar Plexus Block on Cognitive Function in Patients after Knee Joint Replacement. JOURNAL OF CLINICAL RESEARCH, 2020, 37(10): 1514-1516.
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2020, Vol. 37 
