Abstract：【Objective】To investigate the efficacy of direct percutaneous coronary intervention (PCI) in the treatment of acute myocardial infarction (AMI) with type 2 diabetes mellitus. 【Methods】 One hundred and forty-two patients with AMI in our hospital were selected, including 41 patients with type 2 diabetes mellitus (observation group) and 101 patients without type 2 diabetes mellitus (control group), the near and long term major adverse cardiovascular events (MACE) were compared between the two groups. 【Results】There was no significant difference between the two groups in infarct location, culprit vessel, operation time and TIMI blood flow grade 2-3 (P>0.05). The proportion of multiple vessel lesions and the number of stents implanted in the observation group were significantly higher than those in the control group (P<0.05). The incidence of heart failure in the observation group was significantly higher than that in the control group (P<0.05) in one month after treatment (P<0.05). The incidence of failure and stent restenosis was significantly higher than that of control group (P<0.05). 【Conclusion】The pathological changes of AMI patients with type 2 diabetes mellitus are more serious than those without diabetes mellitus, and the incidence of MACE in the near and long term is higher.
[1] 徐伟豪,郭文杰.糖尿病对急性心肌梗死患者PCI术后远期生存的影响[J].解放军医药杂志,2017,29(3):57-61. [2] Fitchett D,Inzucchi S,Lachin J,et al.10-Effect of Empagliflozin on Mortality and Causes of Death in Patients with Type 2 Diabetes at High Cardiovascular Risk[J].Canadian J Card,2016,32(10):S80-S81. [3] Abdelmoneim AS,Eurich DT,Senthilselvan A,et al.Dose‐response relationship between sulfonylureas and major adverse cardiovascular events in elderly patients with type 2 diabetes[J].Pharmacoepidemiol Drug Saf,2016,25(10):1186-1195. [4] Wu JHY,Foote C,Blomster J,et al.Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events,death,and major safety outcomes in adults with type 2 diabetes: a systematic review and meta-analysis[J].Lancet Diabetes Endocrinol,2016,4(5):411-419. [5] 徐伟豪,郭文杰.糖尿病对急性心肌梗死患者PCI术后远期生存的影响[J].解放军医药杂志,2017,29(3):57-61. [6] 陈贝健,孙昊,李惟铭,等.老年急性心肌梗死患者急诊介入治疗术后合并抑郁的影响因素及预后分析[J].中国医师进修杂志,2016,39(4):329-332. [7] 周骏,朱海,秦忠.替罗非班在老年糖尿病合并AMI经皮冠状动脉介入治疗中的价值及安全性评价[J].中西医结合心脑血管病杂志,2016,14(2):158-160. [8] 王雪莉,侯新毅.老年女性急性心肌梗死合并2型糖尿病患者行急诊PCI术临床疗效观察[J].医学临床研究,2016,33(12):2420-2423. [9] Zinman B,Inzucchi SE,Lachin J M,et al.Empagliflozin and cerebrovascular events in patients with type 2 diabetes mellitus at high cardiovascular risk[J].Stroke,2017,48(5):1218-1225.
2019, Vol. 36 
