Abstract：Objective To explore the clinical effect of small tidal volume (VT) ventilation combined with pulmonary resuscitation in the treatment of acute respiratory distress syndrome (ARDS).Methods Thirty-one ARDS patients treated in our hospital from January 2013 to July 2015 were selected. VT (VT= 6 mL/kg, frequency 15~20 times/minute, respiratory ratio=1∶2) ventilation combined with positive end-expiratory pressure increment was used to treat pulmonary reexpansion. The changes of blood gas, mechanical ventilation and adverse reactions before and after 30 minutes of pulmonary reexpansion were compared. Results There was no significant difference in pH value, PaCO2 level, PEEP and tidal volume between pre-and post-pulmonary reexpansion patients (P>0.05). After pulmonary reexpansion, the arterial partial pressure of oxygen (PaCO2) and oxygenation index (OI) increased significantly, and the inhaled oxygen concentration (FiO2) decreased significantly (P<0.05), compared with pre-pulmonary reexpansion patients (P<0.05). After reopening, the plateau pressure was significantly reduced, and the static lung compliance was significantly improved, which was significantly different from that before reopening (P<0.05). No adverse reactions occurred after reopening. Conclusion VT ventilation combined with pulmonary resuscitation in the treatment of ARDS patients can significantly improve PaCO2 and OI, reduce FiO2 levels, thus effectively improve the patient's hypoxemia.
邓美瑶, 程连房. 小潮气量通气联合肺复张术治疗ARDS患者的疗效观察[J]. 医学临床研究, 2019, 36(2): 285-290.
DENG Mei-yao, CHENG Lian-fang. Observation on the Curative Effect of Small Tidal Volume Ventilation Combined with Pulmonary Reexpansion in the Treatment of ARDS. JOURNAL OF CLINICAL RESEARCH, 2019, 36(2): 285-290.
2019, Vol. 36 
