Abstract：【Objective】To research the relationship between premature respiratory secretions of ureaplasma urea original body and neonatal lung injury.【Method】 A total of 246 cases of premature infants with respiratory symptoms in the neonatal intensive care unit in the Maternal and Child Health Hospital of Hunan Province from January 2014 to August 2015 were selected as the research object. The clinical data of each child was recorded in detail. According to the test results of fluorescent quantitative PCR detection of Uu nucleic acid with stomach and, pharyngeal airway secretions which were taken when they were admitted to this hospital, the patients were categorized into a positive group and a negative group. Basic clinical characteristics, infection markers, neonatal respiratory distress syndrome (RDS), congenital pneumonia, and the incidence of bronchial pulmonary dysplasia (BPD) and the length of hospital stay of the two groups were compared.【Result】 In the 246 cases of premature infants, 59 cases of Uu were positive and 187 cases of Uu were negative. In the Uu positive group, incidence of neonatal respiratory distress syndrome was 32.2% (19/59), while in the negative group, it was 45.5% (85/187). Incidence of congenital pneumonia in the Uu positive group was 35.6% (21/59), while incidence in the negative group was 21.9% (46/187). After more than 28 days in the hospital, the incidence of bronchial pulmonary dysplasia in the Uu positive group was 16.9% (10/59), while incidence in the negative group was 8.02% (15/187). The length of hospitalization in the Uu positive group was obviously longer than in the Uu negative groups; the difference had statistical significance.【Conclusions】 For preterm infants, Uu positivity in respiratory secretions increased the incidence of congenital pneumonia and bronchial pulmonary dysplasia, which extended the length of hospital stay. So, it is a protective factor of neonatal respiratory distress syndrome.
范礼英;周利平. 早产儿呼吸道分泌物解脲脲原体阳性与新生儿肺损伤的关系[J]. 医学临床研究, 2016, 33(12): 2329-2332.
FAN Li-ying, ZHOU Li-ping. Analysis of the Relationship between Premature Respiratory Secretions of Ureaplasma Urea Original Body and Neonatal Lung Injury. JOURNAL OF CLINICAL RESEARCH, 2016, 33(12): 2329-2332.
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