Effects of Individualized Nutritional Management Strategy Combined with Comprehensive Intervention Measures on Nutritional Status, Liver Function and Incidence of Complications in Patients with Liver Cirrhosis
MA Lei
Zhoukou First People's Hospital,Zhoukou Henan 466700
Abstract：【Objective】To explore the effects of individualized nutritional management strategy combined with comprehensive intervention measures on nutritional status, liver function and incidence of complications in patients with liver cirrhosis.【Methods】A total of 92 patients with liver cirrhosis admitted to our hospital from January 2023 to January 2024 were selected and divided into the observation group and the control group according to random number table method, with 46 cases in each group. The control group was given routine intervention, and the observation group was given individualized nutritional management strategy combined with comprehensive intervention measures on the basis of routine intervention. The liver function indexes [total bilirubin (TBIL), alanine aminotransferase (ALT), aspartate aminotransferase (AST)], nutritional indexes [body mass index (BMI), mid-arm muscle circumference (MAMC), albumin (ALB), prealbumin (PAB)], incidence of complications (gastrointestinal bleeding, hepatic encephalopathy, hepatorenal syndrome, ascites), and quality of life [Chronic Liver Disease Questionnaire (CLDQ) score] were compared between the two groups before intervention and 1 month after discharge. 【Results】After intervention, the serum levels of TBIL, ALT and AST in both groups were lower than those before intervention, and the observation group was lower than the control group, with statistically significant differences (P<0.05). After intervention, BMI, MAMC, ALB and PAB in both groups were significantly higher than those before intervention, and the observation group was higher than the control group, with statistically significant differences (P<0.05). The total incidence of complications in the observation group was lower than that in the control group, with a statistically significant difference (P<0.05). After intervention, the scores of fatigue, abdominal symptoms, systemic symptoms, emotional function, social function and vitality in both groups were higher than those before intervention, and the observation group was higher than the control group, with statistically significant differences (P<0.05). 【Conclusion】 Individualized nutritional management strategy combined with comprehensive intervention measures can improve liver function indexes and nutritional status of patients with liver cirrhosis, enhance their quality of life, and reduce the incidence of complications.
马蕾. 个体化营养管理策略联合综合干预措施对肝硬化患者营养状态、肝功能及并发症发生率的影响[J]. 医学临床研究, 2025, 42(7): 1202-1205.
MA Lei. Effects of Individualized Nutritional Management Strategy Combined with Comprehensive Intervention Measures on Nutritional Status, Liver Function and Incidence of Complications in Patients with Liver Cirrhosis. JOURNAL OF CLINICAL RESEARCH, 2025, 42(7): 1202-1205.
2025, Vol. 42 
