Abstract：【Objective】 To investigate the effect of coaxial micro incision phacoemulsification on corneal endothelial cell injury and repair.【Methods】 A total of 423 cataract patients who were treated in our hospital from January 2017 to December 2017 were selected and divided into two groups according to the size of incision, including 221 cases in standard incision group (3.0 mm) and 202 cases in micro incision group (1.8-2.2 mm);corneal endothelial cell density, coefficient of variation and morphology of corneal endothelial cells were examined by corneal endothelial microscope and compared before operation, 1 day, 1 week, 1 month and 3 months after operation.【Results】 Before operation, there were no significant differences in corneal endothelial cell density, coefficient of variation, proportion of hexagonal cells and central corneal thickness between the two groups (P>0.05). The corneal endothelial cell density at 7 days and 3 months after operation in the two groups were significantly higher than that before operation, the variation coefficient of corneal endothelial cells was significantly higher than that before operation, and the proportion of hexagonal cells was significantly lower than that before operation (P<0.05). At 7 days after operation, the density of corneal endothelial cells in the micro incision group was significantly higher than that in the standard incision group; the proportion of hexagonal cells in the micro incision group was higher than that in the standard incision group, and the difference was statistically significant (P<0.05); at 3 months after operation, there was no statistical significance in the corneal endothelial cell density and hexagonal cell (P>0.05). There was no significant difference in the coefficient of variation of corneal endothelial cells and central corneal thickness at 7 days and 3 months after operation (P>0.05).【Conclusion】 Compared with conventional incision, coaxial micro incision phacoemulsification has less damage to corneal endothelial cells and faster postoperative recovery, which is worthy of clinical application.
2020, Vol. 37 
