Abstract：【Objective】 To explore the application effect of safflower extract combined with vacuum sealing drainage in the treatment of patients with chronic infected wounds. 【Methods】 A total of 80 patients with chronic infected wounds admitted to our hospital from October 2023 to March 2024 were selected and divided into observation group and control group by random number table method, with 40 cases in each group. The observation group was treated with safflower extract combined with vacuum sealing drainage for wound management, while the control group received conventional debridement, dressing change combined with vacuum sealing drainage. The wound healing rate, pain degree [Visual Analogue Scale (VAS) score] and quality of life [Wound Quality of Life Scale (Wound-QoL) score] were compared between the two groups. 【Results】 At 1, 2 and 4 weeks after treatment, the wound healing rates of the observation group were (17.46±6.28)%, (36.51±8.34)% and (60.32±10.47)% respectively, which were significantly higher than (8.20±4.97)%, (21.31±7.12)% and (37.70±9.65)% of the control group (P<0.05). The VAS scores of the observation group at 1, 2 and 4 weeks after treatment were (4.8±1.1), (3.2±0.9) and (1.8±0.7), significantly lower than (5.6±1.2), (4.9±1.1) and (3.9±0.8) in the control group (P<0.05). The Wound-QoL scores of the observation group were significantly better than those of the control group at each time point after treatment (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Safflower extract combined with vacuum sealing drainage has a remarkable clinical effect in treating chronic infected wounds. It can promote wound healing, relieve pain and improve quality of life, which provides an effective method for the management of chronic infected wounds.
汤江华, 王素娟, 王海燕. 红花浸提液联合负压封闭引流在慢性感染伤口患者治疗中的应用效果*[J]. 医学临床研究, 2026, 43(5): 713-715.
TANG Jianghua, WANG Sujuan, WANG Haiyan. Application Effect of Safflower Extract Combined with Vacuum Sealing Drainage in the Treatment of Patients with Chronic Infected Wounds. JOURNAL OF CLINICAL RESEARCH, 2026, 43(5): 713-715.
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2026, Vol. 43 
