苏州市吴中区2021年至2024年新生儿先天性心脏病筛查结果分析

doi:10.3969/j.issn.1671-7171.2025.05.031

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摘要【目的】分析苏州市吴中区2021年至2024年新生儿先天性心脏病(CHD)筛查情况。【方法】回顾性分析2021年1月至2024年12月苏州市吴中区登记的11 816名活产新生儿及其产妇的相关一般资料,统计登记人数、筛查人数及筛查率,筛查阳性人数及初筛阳性率,心脏超声诊断人数及诊断率,确诊CHD人数及确诊率,以及接受手术治疗的人数和治疗结果。【结果】2021年至2024年苏州市吴中区CHD新生儿及产妇一般资料比较,差异无统计学意义(P>0.05)。四年间共登记新生儿11 816例,实际筛查11 807例,筛查率为99.92%。2021年至2024年期间筛查率基本不变,但初筛阳性率有所下降,初筛阳性CHD确诊率明显升高(P<0.05)。苏州市吴中区2021年至2024年新生儿CHD分型比较,差异无统计学意义(P>0.05)。105例CHD患儿中,治愈25例,手术治疗3例,死亡2例,其余截至随访结束未治愈。【结论】苏州市吴中区新生儿CHD筛查工作在2021年至2024年期间维持在高水平,初筛阳性率下降,初筛阳性CHD确诊率和心脏超声诊断率稳定。

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	姚晨华
	施茜

关键词 ：心脏缺损,先天性, 婴儿,新生, 新生儿筛查

Abstract：【Objective】To analyze the screening situation of congenital heart disease (CHD) in neonates in Wuzhong District, Suzhou City from 2021 to 2024. 【Methods】A retrospective analysis was conducted on the relevant general data of 11,816 live newborns and their parturients registered in the Wuzhong District, Suzhou City from January 2021 to December 2024.The number of registered people, the number of screened people and the screening rate, the number of positive screening people and the initial screening positive rate, the number of people diagnosed by cardiac ultrasound and the diagnosis rate, the number of people diagnosed with CHD and the diagnosis rate, as well as the number of people who received surgical treatment and the treatment outcome were statistically analyzed.【Results】There was no statistically significant difference in the general data of neonates and parturients with CHD in the Wuzhong District, Suzhou City from 2021 to 2024 (P>0.05). A total of 11 816 newborns were registered during the four years, and 11 807 were actually screened, with a screening rate of 99.92%. During the period from 2021 to 2024, the screening rate remained basically unchanged, but the positive rate of the initial screening decreased somewhat, and the diagnosis rate of positive pre-existing heart disease in the initial screening increased significantly (P<0.05). The comparison of CHD classification of newborns in Wuzhong District, Suzhou City from 2021 to 2024 showed no statistically significant difference (P>0.05). Among the 105 children with CHD, 25 were cured, 3 underwent surgical treatment, 2 died, and the rest remained uncured by the end of the follow-up. 【Conclusion】The neonatal CHD screening work in Wuzhong District, Suzhou City remained at a high level during the period from 2021 to 2024. The positive rate of the initial screening decreased, while the diagnosis rate of positive CHD in the initial screening and the diagnosis rate by echocardiography remained stable.

Key words： Heart Defects, Congenital Infant, Newborn Neonatal Screening

收稿日期: 2025-03-05

中图分类号:

R725.411

通讯作者: *E-mail:13776161582@163.com

引用本文:

姚晨华, 施茜. 苏州市吴中区2021年至2024年新生儿先天性心脏病筛查结果分析[J]. 医学临床研究, 2025, 42(5): 844-847.
YAO Chenhua, SHI Qian. Analysis of the Screening Results of Congenital Heart Disease in Newborns in the Wuzhong District, Suzhou City from 2021 to 2024. JOURNAL OF CLINICAL RESEARCH, 2025, 42(5): 844-847.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2025.05.031 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2025/V42/I5/844

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