Abstract：【Objective】To investigate the risk factors of relapse in children with epilepsy after drug treatment. 【Methods】The clinical data of 90 children with epilepsy admitted to our hospital from May 2020 to May 2021 were retrospectively analyzed, and they were divided into the observation group (children with relapse) and the control group (children without relapse) according to the recurrence of epilepsy after drug treatment. Logistic multivariate regression analysis was used to investigate the independent risk factors of relapse after drug treatment in children with epilepsy. 【Results】There were 24 cases of recurrence in 90 cases, the recurrence rate was 26.67%. Univariate analysis showed that there were statistically significant differences in age, frequency of onset, type of disease, duration of epilepsy, intracranial lesions and seizure free time before drug withdrawal between the two groups (P<0.05). Multivariate Logistic regression analysis showed that age (< 2 years), duration of disease before treatment ( >1 year), duration of drug withdrawal (< 6 months), and ECG after drug withdrawal showed that epileptic discharge were independent risk factors for relapse after drug treatment in children with epilepsy (P<0.05). 【Conclusion】 Age, course of disease before treatment, duration of drug withdrawal, eclamptic discharge shown by ECG after drug withdrawal are important risk factors for relapse in children with epilepsy after drug treatment. Clinical preventive measures can be taken according to risk factors to reduce the recurrence rate of epilepsy after drug treatment and improve the quality of life of children with epilepsy.
李炎炎, 张晓立, 戴冬晴, 聂富英. 癫痫儿童药物治疗后复发的危险因素及预防对策分析[J]. 医学临床研究, 2024, 41(12): 1924-1926.
LI Yanyan, ZHANG Xiaoli, DAI Dongqing, et al. Analysis of Risk Factors and Preventive Measures of Relapse in Children with Epilepsy after Drug Treatment. JOURNAL OF CLINICAL RESEARCH, 2024, 41(12): 1924-1926.
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2024, Vol. 41 
