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| Multivariate Analysis of the Relationship between Tp-Te Interval, Serum Phosphate Concentration and Prognosis of HFpEF Patients |
| YU Yan-yan, WANG Wen-zhi, WU Cong |
| Shandong Provincial Third Hospital,Jinan Shandong,250000,China |
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Abstract 【Objective】To investigate the correlation between T-peak to end interval (Tp-Te interval) of ECG, serum phosphate level and the prognosis of patients with ejection fraction preserved heart failure (HFPEF). 【Methods】 A total of 98 patients with HFPEF treated in our hospital from January 2018 to March 2020 were divided into observation group (poor prognosis, mace, n=20) and control group (good prognosis, no mace, n=78). The levels of serum phosphate, NT-proBNP and cardiac function were compared between the two groups, and the risk factors of mace in patients with HFPEF were analyzed. 【Results】 The Tp-Te interval in the observation group was longer than that in the control group, and the levels of serum phosphate and NT-proBNP were significantly higher than those in the control group (P<0.05). VST and LVPWT in the observation group were significantly higher than those in the control group (P<0.05); There was no significant difference in LVEF and LVEDd between the two groups (P>0.05). Pearson correlation analysis showed that Tp-Te interval was positively correlated with NT- proBNP, VST and LVPWT (r=0.333, 0.356 and 0.329, Mean P<0.05), and serum phosphate concentration was positively correlated with NT-proBNP (r=0.350, P<0.05). Logistic regression analysis showed that long Tp-Te interval, high serum phosphate level and VST were the risk factors for MACE in patients with hfpee (OR=1.406, 1.426, 1.603, Mean P<0.05). 【Conclusion】 Too long Tp-Te interval, too high serum phosphate level and too thick VST are the risk factors of MACE in patients with HFpEEh. These patients should be given timely and effective treatment measures to reduce the incidence of MACE.
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Received: 22 May 2020
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2021, Vol. 38 
