自拟苦参坐浴熏洗方应用于混合痔术后肛门创面的临床疗效<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2024.10.011

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (1248 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要【目的】探讨自拟苦参坐浴熏洗方对混合痔患者术后肛门创面恢复及血清炎症因子水平的影响。【方法】回顾性分析2022年6月至2024年6月本院收治的80例混合痔患者的临床资料,根据治疗方法不同将其分为观察组和对照组,每组40例。两组均接受混合痔外剥内扎手术。对照组术后采用高锰酸钾溶液肛门创面熏洗坐浴,观察组术后采用自拟苦参坐浴熏洗方肛门创面熏洗坐浴,持续治疗4周。比较两组患者的临床疗效、疼痛程度[疼痛视觉模拟法(VAS)评分]、肛门创面恢复情况[创面渗液评分、创面面积评分、创面愈合时间]和血清炎症因子[C-反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平。【结果】观察组的总有效率高于对照组,差异有统计学意义(P<0.05)。与同组术后1 d比较,术后3 d、7 d的VAS评分均显著降低,且观察组低于对照组,差异有统计学意义(P<0.05)。与同组术后1 d比较,两组术后3 d、7 d创面渗液评分、创面面积评分均显著降低,且观察组低于对照组(P<0.05)。观察组创面愈合时间显著短于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者血清IL-6、CRP、TNF-α水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。【结论】自拟苦参坐浴熏洗方能显著促进混合痔患者肛门创面的愈合,减轻炎症反应,是一种有效的术后辅助治疗方法。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词 ：痔/外科学, 痔/中医药疗法, 伤口愈合, 治疗结果

Abstract：【Objective】To investigate the effect of matrine sit-bath fumigating decoction on postoperative anal wound recovery and serum inflammatory factors in patients with mixed hemorrhoids.【Methods】The clinical data of 80 patients with mixed hemorrhoids admitted to our hospital from June 2022 to June 2024 were retrospectively analyzed, and they were divided into the observation group and the control group according to treatment methods, with 40 cases in each group. Both groups received mixed hemorrhoid external stripping and internal ligation. The control group was treated with potassium permanganate solution anal wound bath after operation, and the observation group was treated with self-designed matrine sat bath after operation for 4 weeks. The clinical efficacy, pain degree [visual analogue of pain (VAS) score], anal wound recovery (wound efflux score, wound area score, wound healing time) and serum inflammatory factors [C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)] were compared between the two groups. 【Results】The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). Compared with the same group 1 day after surgery, the VAS scores at 3 and 7 days after surgery were significantly decreased, and the observation group was lower than the control group, the difference was statistically significant (P<0.05). Compared with the same group 1 day after surgery, the wound permeability score and wound area score of the two groups were significantly decreased at 3 and 7 days after surgery, and the observation group was lower than the control group (P<0.05). The wound healing time in the observation group was significantly shorter than that in the control group, and the difference was statistically significant (P<0.05). After treatment, serum levels of IL-6, CRP and TNF-α in 2 groups were lower than before treatment, and the observation group was lower than control group, the difference was statistically significant (P<0.05). 【Conclusion】The Self-made matrine sit-bath fumigation can significantly promote the healing of anal wounds in patients with mixed hemorrhoids, reduce inflammation, and is an effective adjuvant treatment.

Key words： Hemorrhoids/SU Hemorrhoids/ZY Wound Healing Treatment Outcome

收稿日期: 2024-08-28

中图分类号:

R657.18

基金资助:^*上海市青浦区卫生健康委员会科研项目(QKY2022-29)

通讯作者: **E-mail:bones11@sina.com

引用本文:

赵贇, 季顺祥, 陈晓平, 丁婷, 许文彬. 自拟苦参坐浴熏洗方应用于混合痔术后肛门创面的临床疗效^*[J]. 医学临床研究, 2024, 41(10): 1494-1496.
ZHAO Yun, JI Shunxiang, CHEN Xiaoping, et al. Effect of Self-made Matrine Sit-Bath Fumigation-washing Formula on Postoperative Anal Wound Recovery and Serum Inflammatory Factor Levels in Patients with Mixed Hemorrhoids. JOURNAL OF CLINICAL RESEARCH, 2024, 41(10): 1494-1496.

链接本文:

http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2024.10.011 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2024/V41/I10/1494

[1] 王翔,张峰,李杨春. 改良生肌玉红膏联合枳壳汤对混合痔术后创面恢复的影响[J].医学临床研究,2023,40(8):1232-1234.
[2] 洪子夫,冯丽鹏,何颖华,等. 改良外剥内扎楔形切除整形术加消痔灵注射术治疗环状混合痔临床研究[J].中国临床医生杂志,2023,51(2):225-227.
[3] 林子栋,席作武,刘洪波. SIRT1在复方苦参汤抑制溃疡性结肠炎小鼠氧化损伤和炎性反应中的作用[J].中成药,2023,45(2):415-422.
[4] 中华中医药学会发布.中医肛肠科常见病诊疗指南[M].北京:中国中医药出版社,2012:10-13.
[5] 国家中医药管理局医政司.《中医病证诊断疗效标准》[J].湖北中医杂志,2002,24(2):57.
[6] 何姗姗,张庆. 老年良性前列腺增生合并混合痔患者术后尿潴留的影响因素分析[J].老年医学与保健,2023,29(5):1057-1060.
[7] 龚璇,唐慧娟,蒋维连,等. 混合痔患者术后早期疼痛信念现状及其影响因素分析[J].中国实用护理杂志,2022,38(9):681-686.
[8] 江波,王祥琨,贺磊,等. 混合痔患者行吻合器切除术后慢性疼痛发生危险因素及风险模型的建立[J].贵州医科大学学报,2022,47(1):96-100.
[9] 周浩忠,史月凡,张如洁,等. 中西医治疗混合痔术后肛缘水肿的研究进展[J].中国中西医结合外科杂志,2023,29(3):393-397.
[10] 余汉辉,梅锋,俞金龙. PPH术联合外痔切除一期缝合辅助痔疮洗液熏蒸治疗混合痔的效果评价[J].现代中西医结合杂志,2021,30(34):3822-3825.
[11] 许爱军. 痔清舒洗剂熏洗坐浴在混合痔术后的临床应用[J].生命科学仪器,2023,21(S1):338.
[12] 陈晓平,许文彬,赵贇. 苦参汤熏洗疗法对混合痔术后患者创面愈合及并发症的影响观察[J].贵州医药,2022,46(4):609-610.
[13] 黄海鹏,简弄根,黄红根,等. 苦参汤加减熏洗对混合痔外剥内扎术后创面愈合、疼痛及肛门功能的影响[J].河南中医,2023,43(2):286-289.
[14] 周莉莉. 苦参汤加减熏洗联合紫黄生肌膏对混合痔患者术后创面恢复及对生长因子和炎症因子的影响[J].临床与病理杂志,2023,43(2):302-309.