Effect of Non-Insufflated and Insufflated Transaxillary Endoscopic Thyroidectomy on Recurrent Laryngeal Nerve Injury and Prognosis in Patients with Differentiated Thyroid Carcinoma
CHEN Yalin, WANG Xiaobin, WANG Jing, et al
Qingdao Central Hospital, Rehabilitation University Qingdao Center Hospital,Qingdao Shandong 266042
Abstract：【Objective】 To investigate the effect of non-insufflated and insufflated transaxillary endoscopic thyroidectomy on recurrent laryngeal nerve (RLN) injury and prognosis in patients with differentiated thyroid carcinoma (DTC).【Methods】 Eighty-eight DTC patients undergoing transaxillary endoscopic thyroidectomy in our hospital were divided into a non-insufflated group (40 cases) and an insufflated group (48 cases) according to the different surgical methods. The levels of parathyroid hormone (PTH), recurrence rate, operation time, hospital stay, blood loss, drainage volume, incidence of RLN injury, and quality of life (QOL) scores were compared between the two groups.【Results】 Postoperatively, the PTH level in the non-insufflated group was higher than that in the insufflated group (P<0.05). There was no statistically significant difference in the recurrence rates between the two groups (P>0.05). The operation time and hospital stay were shorter, and the blood loss and drainage volume were less in the non-insufflated group than in the insufflated group. The incidence of temporary RLN injury was lower in the non-insufflated group (P<0.05). At three months post-operation, the QOL scores in the non-insufflated group were higher than those in the insufflated group (P<0.05).【Conclusion】 Compared to insufflated surgery, non-insufflated transaxillary endoscopic thyroidectomy can shorten the operation and hospital stay, reduce blood loss and drainage volume, and lower the incidence of temporary RLN injury. Additionally, patients have better quality of life postoperatively, making it worthy of clinical promotion and application.
陈亚琳, 王晓彬, 王晶, 李妙玉. 无充气与充气经腋窝入路腔镜切除术对分化型甲状腺癌喉返神经损伤及预后的影响[J]. 医学临床研究, 2024, 41(8): 1135-1137.
CHEN Yalin, WANG Xiaobin, WANG Jing, et al. Effect of Non-Insufflated and Insufflated Transaxillary Endoscopic Thyroidectomy on Recurrent Laryngeal Nerve Injury and Prognosis in Patients with Differentiated Thyroid Carcinoma. JOURNAL OF CLINICAL RESEARCH, 2024, 41(8): 1135-1137.
[1] 谢磊,柴凡,鲍刚,等. 血清Tg、TgAb对甲状腺癌根治术联合131I治疗后随访期间复发/转移的评估价值[J].中国现代医学杂志,2023,33(19):74-79. [2] 张晓杰,胡张艳,魏卓亚. 经腋窝入路腔镜下甲状腺切除术治疗结节性甲状腺肿患者的临床研究[J].医药论坛杂志,2020,41(3):107-110. [3] 马震,王薇,耿中利. 无充气与充气经腋窝入路腔镜甲状腺癌切除术技术的比较[J].四川医学,2022,43(4):369-373. [4] 刘凯,刘伟,刘昊中,等. 老年甲状腺开放手术患者喉返神经损伤的相关因素及其预防[J].中国老年学杂志,2023,43(19):4717-4721. [5] 何石养,张勇军,梁亚平,等. 甲状腺恶性肿瘤术后难治性低钙血症一例并文献复习[J].遵义医科大学学报,2023,46(11):1111-1115. [6] 刘奋琴,尚惠,徐红英. 盆底磁刺激联合中医理疗对压力性尿失禁患者漏尿量及盆底肌张力的影响[J].医学临床研究,2023,40(1):57-60. [7] DROZD V, SAENKO V, BRANOVAN D I, et al. A search for causes of rising incidence of differentiated thyroid cancer in children and adolescents after Chernobyl and Fukushima: Comparison of the clinical features and their relevance for treatment and prognosis[J].Int J Environmental Res Public Health,2021, 18(7): 3444. [8] 张勇跃,王淑敏,梅放,等.2例多结节侵袭性生长滤泡亚型甲状腺乳头状癌超声表现[J].中国医学影像技术,2024,40(2):306-308. [9] 程卫,戚新春,李阳,等. 颈前微切口腔镜甲状腺切除术对分化型甲状腺癌患者的治疗效果[J].癌症进展,2023,21(4):388-390. [10] 朱海军,陈巍,田立民,等. 经环甲隙喉返神经显露法在甲状腺癌术中的应用效果及对声带功能的影响[J].癌症进展,2020,18(11):1123-1126. [11] 王庆艳,王慧慧,刘丽亚. 分化型甲状腺癌再次手术的效果与影响预后的相关因素分析[J].实用癌症杂志,2022,37(8):1283-1285. [12] 林庆军,杜丽,林燕晖,等.分化型甲状腺癌甲状腺全切术中精细化甲状腺被膜解剖术与经环甲隙显露喉返神经法联合应用观察[J].山东医药,2023,63(30):25-28.
2024, Vol. 41 
