Clinical Efficacy of Ultrasound-guided Intervention Therapy with Lauromacrogol Combined with Postoperative Oral Gestrinonein the Treatment of Patients with Ovarian Endometriotic Cysts
JIANG Yongli, LI Kai
Ultrasound Department of the Fufeng County People's Hospital in Shaanxi Province, Baoji Shaanxi 722299
摘要【目的】探讨超声引导下聚桂醇介入治疗联合术后口服孕三烯酮治疗卵巢子宫内膜异位囊肿患者的临床效果。【方法】选取2021年1月至2023年12月在陕西省扶风县人民医院诊治的82例卵巢子宫内膜异位囊肿患者,根据治疗方法不同分为对照组和观察组,每组41例。对照组行超声引导下聚桂醇介入治疗,观察组行超声引导下聚桂醇介入治疗联合术后口服孕三烯酮治疗。比较两组手术指标(手术时间、住院时间)、术后并发症发生情况及术前、治疗后5 d卵巢功能指标[卵泡刺激素(FSH)、黄体生成素(LH)]水平。【结果】观察组住院时间短于对照组(P<0.05)。观察组总有效率为95.12%,显著高于对照组的78.05%(P<0.05)。与术前比较, 两组治疗后5 d FSH、LH水平均升高,但观察组治疗后5 d FSH、LH水平低于对照组(P<0.05)。观察组并发症总发生率为7.32%,显著低于对照组的24.39%(P<0.05)。【结论】超声引导下聚桂醇介入治疗联合术后口服孕三烯酮治疗卵巢子宫内膜异位囊肿患者,效果显著,可促进患者术后恢复,改善卵巢功能,降低并发症发生率。
Abstract:【Objective】To explore the clinical effect of ultrasound-guided intervention with Lauromacrogol combined with postoperative oral Gestrinonein in the treatment of patients with ovarian endometriotic cysts. 【Methods】A total of 82 patients with ovarian endometriotic cysts treated at the People's Hospital of Fufeng County, Shaanxi Province from January 2021 to December 2023 were selected. They were divided into a control group and an observation group based on different treatment methods, with 41 cases in each group. The control group received ultrasound-guided intervention therapy with Lauromacrogol, while the observation group received ultrasound-guided intervention therapy with Lauromacrogol combined with postoperative oral Gestrinonein treatment. Two groups of surgical indicators (surgery time, hospital stay), incidence of postoperative complications, and levels of ovarian function indicators [follicle stimulating hormone (FSH) and luteinizing hormone (LH)] before and 5 days after treatment were compared.【Results】The hospitalization time of the observation group was shorter than that of the control group (P<0.05). The total effective rate of the observation group was 95.12%, significantly higher than 78.05% of the control group (P<0.05). Compared with preoperative treatment, FSH and LH levels increased in both groups 5 days after treatment, but the FSH and LH levels in the observation group were lower than those in the control group 5 days after treatment(P<0.05). The total incidence of complications in the observation group was 7.32%, significantly lower than the control group's 24.39%(P<0.05). 【Conclusion】The combination of ultrasound-guided Lauromacrogol intervention with oral Gestrinonein is effective in treating patients with ovarian endometriotic cysts. It can promote postoperative recovery, improve ovarian function, and reduce the incidence of complications.
姜永利, 李凯. 超声引导下聚桂醇介入治疗联合术后口服孕三烯酮治疗卵巢子宫内膜异位囊肿患者的临床效果[J]. 医学临床研究, 2024, 41(7): 1064-1067.
JIANG Yongli, LI Kai. Clinical Efficacy of Ultrasound-guided Intervention Therapy with Lauromacrogol Combined with Postoperative Oral Gestrinonein the Treatment of Patients with Ovarian Endometriotic Cysts. JOURNAL OF CLINICAL RESEARCH, 2024, 41(7): 1064-1067.
[1] 吴琳,邓茂芳. GnRH-α联合桂枝茯苓丸对卵巢子宫内膜异位囊肿患者腹腔镜术后卵巢储备功能的影响[J].医学临床研究,2021,38(6):893-896. [2] WANG Y P, CHEN L F, SHEN H P, et al. Fimbrial Teratoma presenting as ovarian cyst[J].J Minim Invasive Gynecol,2021, 28(7):1265-1266. [3] ROMEO L, BAGOLINI F, FERRO S, et al. Laparoscopic surgery for splenic injuries in the era of non-operative management: current status and future perspectives[J].Surg Today,2021, 51(7):1075-1084. [4] WANG X D, YANG B, FAN L L, et al. Application of dexmedetomidine combined with propofol intravenous anesthesia in laparoscopic day surgery in pediatric urology[J].Pak J Med Sci,2022, 38(1):150-155. [5] WAKASUGI M, HASEGAWA J, IKEDA Y. Single-incision laparoscopic totally extraperitoneal inguinal hernia repair with tumescent local anesthesia: report of more than 2000 procedures at a day-surgery clinic[J].Surg Today,2021, 51(4):545-549. [6] MCDONALD A M, SPENCER S A, WILLEY C D, et al. Lipid microsphere bound oxycodone for pain management in patients receiving radiotherapy for head and neck cancer[J].Support Care Cancer,2021, 29(1):263-269. [7] XU Y J, SUN X, JIANG H, et al. Randomized clinical trial of continuous transversus abdominis plane block, epidural or patient-controlled analgesia for patients undergoing laparoscopic colorectal cancer surgery[J].Br J Surg,2020, 107(2):133-141. [8] CHIAROTTO A, MAXWELL L J, OSTELO R W, et al. Measurement properties of visual analogue scale, numeric rating scale, and pain severity subscale of the brief pain inventory in patients with low back pain: a systematic review[J].J Pain,2019, 20(3):245-263. [9] EL FAWAL M H, MOHAMMED D A, ABOU-ABBASS H, et al. Laparoscopic sleeve gastrectomy under awake paravertebral blockade versus general anesthesia: comparison of short-term outcomes[J].Obes Surg,2021, 31(5):1921-1928. [10] 谢幸, 孔北华, 段涛.妇产科学[M]. 9版.北京:人民卫生出版社, 2018:582-583. [11] TUSMAN G, WALLIN M, ACOSTA C, et al. Positive end-expiratory pressure individualization guided by continuous end-expiratory lung volume monitoring during laparoscopic surgery[J].J Clin Monit Comput,2022,36(5):1557-1567. [12] EL-BOGHDADLY K, DESAI N, HALPERN S, et al. Quadratus lumborum block vs. transversus abdominis plane block for caesarean delivery: a systematic review and network meta-analysis[J].Anaesthesia,2021, 76(3):393-403. [13] DESAI N, EL-BOGHDADLY K, ALBRECHT E. Epidural vs. transversus abdominis plane block for abdominal surgery - a systematic review, meta-analysis and trial sequential analysis[J].Anaesthesia,2021, 76(1):101-117. [14] LI Y W, LI H J, LI H J, et al. Delirium in older patients after combined epidural-general anesthesia or general anesthesia for major surgery: a randomized trial[J].Anesthesiology,2021, 135(2):218-232. [15] HAMID H K S, MARC-HERNANDEZ A, SABER A A. Transversus abdominis plane block versus thoracic epidural analgesia in colorectal surgery: a systematic review and meta-analysis[J].Langenbecks Arch Surg,2021, 406(2):273-282. [16] IDRIS S, DAUD S, AHMAD S N, et al. A case of twisted ovarian cyst in a young patient and review of the literature[J].Am J Case Rep,2021,17(22):e933438. [17] NOWAK-PSIORZ I, CIECWIEZ S M, BRODOWSKA A, et al. Treatment of ovarian endometrial cysts in the context of recurrence and fertility[J].Adv Clin Exp Med,2019,28(3):407-413. [18] JIANG R J, SUN Y, WANG H M, et al. Effect of different carbon dioxide insufflation for laparoscopic colorectal surgery in elderly patients: a randomized controlled trial[J].Medicine (Baltimore),2019,98(41):e17410. [19] 仲跻凤. 聚桂醇泡沫硬化后超声介入治疗肝、肾及卵巢子宫内膜异位囊肿的临床观察[J].海军医学杂志, 2019, 36(5):416-418. [20] 林洁. 孕三烯酮联合宫瘤清胶囊可提高超声介入对卵巢子宫内膜异位囊肿的治疗[J].基因组学与应用生物学, 2019, 37(2): 519-523. [21] 殷晓颖, 吴曼, 吴腾珍, 等. 超声引导下聚桂醇与无水乙醇介入治疗卵巢子宫内膜异位囊肿的效果比较[J].东南国防医药, 2022, 5(3):24. [22] 王金艳. 腹腔镜联合药物治疗卵巢子宫内膜异位囊肿临床观察[J].中国妇幼保健, 2020, 25(33): 4954-4955.