Abstract:【Objective】To explore the significance of blood pressure pulse wave index monitoring in the perioperative period of general anesthesia in elderly patients undergoing laparoscopic surgery.【Methods】The blood pressure and pulse wave index of 40 elderly patients undergoing general anesthesia and laparoscopic surgery were measured before anesthesia,at the end of operation and one week after operation.The blood pressure and pulse wave data and the changes of blood pressure and heart rate in different operation periods were observed,and the occurrence of postoperative complications was recorded. 【Results】 The brachial ankle pulse wave velocity (baPWV) and ankle brachial index (ABI) in the blood pressure pulse wave index of the patients at the end of the operation were higher than those before anesthesia (P<0.05),but the baPWV and ABI of the patients at the end of the operation had no significant change compared with those before anesthesia (P>0.05).The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were lower than those before endotracheal intubation (P<0.05); After skin cutting and immediately after drug withdrawal,SBP and DBP increased compared with that before endotracheal intubation (P<0.05),but there was no significant difference between them (P>0.05); The heart rate during endotracheal intubation was higher than that before operation (P<0.05),and the heart rate after skin incision and immediately after drug withdrawal was lower than that during endotracheal intubation (P<0.05); But there was no significant difference between them (P>0.05).Only 2 (5.00%) patients had ischemic heart disease,6 (15.00%) patients had hypooxia,4 (10.00%) patients had chills,and the complication rate was 30.00% (12/40). 【Conclusion】The blood pulse wave index,blood pressure and heart rate of the elderly patients during the peri operative period of general anesthesia and laparoscopic surgery have obvious changes,but there are no obvious changes after and before the operation; It indicates that this change can be reversed temporarily.In clinical practice,the blood pulse wave index can be used to monitor the arterial condition of the elderly patients,and intervention treatment can be carried out as soon as possible to alleviate the disease and reduce the occurrence of complications and improve the safety of the operation.