Abstract：【Objective】Based on data from the utilization of wide-area digital fundus imaging system (Retcam Ⅲ) for full-term neonates fundus screening, this thesis aims to explore its application value by systematic analyzing clinical data arrays.【Methods】Clinical data of 3987 full-term newborns in Hunan Provincial Maternal and Child Health Care Hospital from January 2017 to December 2019 were retrospectivelyanalyzed to link Retcam Ⅲ fundus screening results with birth weight and delivery methods. 【Results】Among the 3987 full-term newborns who completed the Retcam Ⅲ examination, a total of 1020 of them had fundus lesions, therefore the abnormality rate was 25.58%.Among those fundus neonates, there were 736 cases of retinal hemorrhage(18.46%), 233 cases of retinal exudative changes (5.84%), 19 cases of suspected familial exudative vitreoretinopathy(0.48%), 13 cases of retinal pigmented nevus(0.33%), 8 cases of albinism with fundus change(0.20%), 6 cases of loss of retinal pigment(0.15%), 6 cases of persistent fetal vasculature (0.15%),3 cases of choroidal coloboma(0.08%),2 cases of retinoschisis (0.05%) and 1 case of retinoblastoma(0.03%). Neonatal retinal hemorrhage was associated with mode of delivery and birth weight (P<0.05).The incidence of blinding eye diseases accounted for 0.78% (31/39870), including 19 cases of familial exudative vitreoretinopathy, 6 cases of persistent fetal vasculature, 3 cases of choroidal coloboma, 2 cases of retinoschisis and 1 case of retinoblastoma.【Conclusion】Various types of fundus lesions can appear in full-term neonates with a rather high rate of abnormal screening incidence. The utilization of Retcam Ⅲ is a very efficient method for fundus defects early detection and diagnosis to give patients a better chance to avoid blindness and low vision.
2022, Vol. 39 
