Abstract：【Objective】To explore the curative effect of periodontal treatment at different time after root canal therapy in patients with combined periodontal and pulp lesions. 【Methods】A total of 120 patients with combined periodontal and pulp lesions from October 2018 to October 2019 were selected as the research object. Patients were randomly divided into the observation group and the control group with 60 cases in each group. Both groups received periodontal treatment after root canal treatment. Patients in the observation group received periodontal treatment in 1 week after root canal treatment and patients in the control group received periodontal treatment in 3 weeks after the root canal treatment . The clinical efficacy of the two groups were compared 5 weeks after treatment, and the differences of periodontal probing depth (PD), attachment loss level (AL), gingival retreat (RG) and plaque index (PLI) before and after treatment were compared between the two groups as well. In addition, interleukin-8 (IL-8), interleukin-6 (IL-6) and interleukin-1 β (IL-1β) levels in gingival crevicular fluid and serum were compared between the two groups before and after operation. 【Results】The total effective rate of observation group was 91.66%(55/60), and there was no statistical significance compared with 88.33%(53/60) of control group (P>0.05). The levels of PD, AL and PLI in the two groups were significantly decreased and the level of RG was significantly increased after treatment, and the differences were statistically significant (P<0.05). The levels of PD, AL and PLI in the observation group were significantly lower than those in the control group after treatment, and the differences were statistically significant (P<0.05). Compared to before operation, levels of IL-8, IL-1β and IL-6 in gingival crevicular fluid and serum in both groups decreased significantly after operation with statistical significance (P<0.05), while levels of IL-8, IL-1β and IL-6 in observation group were lower than those in control group after operation and the difference was statistically significant (P<0.05). 【Conclusion】Root canal therapy combined with early periodontal treatment can better improve the levels of PD, AL, PLI, IL-8, IL-1β and IL-6 in patients of combined periodontal and pulp lesions, which is worthy of clinicians' attention.
林兴伟, 王迎捷, 王博. 牙周牙髓联合病变患者根管治疗后不同时机进行牙周治疗的疗效观察[J]. 医学临床研究, 2021, 38(12): 1853-1856.
LIN Xing-wei, WANG Ying-jie, WANG Bo. Curative Observation of Different Time Periodontal Treatments after Root Canal Therapy in Patients with combined Periodontal and Pulp Disease. JOURNAL OF CLINICAL RESEARCH, 2021, 38(12): 1853-1856.
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2021, Vol. 38 
