Abstract：【Objective】To analyze the clinical data of 381 patients with colorectal cancer in our hospital, so as to explore the opportunistic screening strategy of colorectal cancer. 【Methods】 The clinical data of 381 patients with colorectal cancer in our hospital from January 2014 to December 2019 were analyzed retrospectively. The demographic characteristics, biochemical data and histological types of patients were analyzed. The age distribution, location and histological types of colorectal cancer patients of different genders were compared, and the high-risk factors of colorectal cancer patients were analyzed.【Results】The ratio of male to female in 381 patients was 1.23∶1. The proportion of 61~70 years old was the highest (30.4%), followed by 71~80 years old (21.8%) and 51 ~ 60 years old (21.3%). There was no significant difference in the age distribution of colorectal cancer patients between different genders(χ2=1.166,P=0.979>0.05). There was no significant difference in the age of colorectal cancer between different genders (P>0.05). The most common location was rectosigmoid colon (272 cases, 71.4%), and the most common histological type was adenocarcinoma (288 cases, 75.6%). There was no significant difference in the location and histological type of colorectal cancer between different genders (P>0.05). There was no significant difference in the location and histological type of colorectal cancer at different ages (P>0.05). The investigation data of 114 patients with high-risk factors were complete, with a total of 191 high-risk factors, among which FOBT positive and abnormal defecation were the most common. Among 114 patients, 110 (96.5%) had high-risk factors, and more than two high-risk factors accounted for 74.5%. 【Conclusion】 The proportion of colorectal cancer under 50 years old is high, and there is little difference in the age, location and type of colorectal cancer between different genders. Age and gender restrictions should not be made for opportunistic screening. The opportunistic screening of colorectal cancer should pay attention to the population with positive FOBT test, abnormal defecation and more than two high-risk factors.
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2021, Vol. 38 
