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医学临床研究  2021, Vol. 38 Issue (4): 553-555    DOI: 10.3969/j.issn.1671-7171.2021.04.021
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罗哌卡因复合右美托咪定连续股神经阻滞对老年全膝关节置换患者的效果
朱明霞1, 何花丽2*
1.陕西省西安市第四医院麻醉科,陕西 西安 710004;
2.陕西中医药大学附属医院手术麻醉科,陕西 咸阳 712000
Ropivacaine Compounded with Dexmedetomidine Continuous Femoral Nerve Block in Elderly Patients undergoing Total Knee Replacement
ZHU Ming-xia, HE Hua-li
Department of Anesthesiology, the Fourth Hospital of Xi'an,Xi'an 710004, Shaanxi
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摘要 【目的】 探讨罗哌卡因复合右美托咪定连续股神经阻滞对老年全膝关节置换患者镇痛效果、睡眠质量和术后谵妄的影响。【方法】 将在本院治疗的106例老年全膝关节置换患者随机分为对照组和观察组,每组53例。两组患者均在超声引导下行连续股神经阻滞,对照组给予0.2%罗哌卡因200 mL,观察组给予0.2%罗哌卡因200 mL+4 μg/kg右美托咪定。比较两组的镇痛效果、睡眠质量、术后谵妄及术后并发症发生情况。【结果】 与对照组比较,观察组术后d1、d2、d3的数字分级量表(NRS)和ICU谵妄评估表(CAM-ICU)评分均明显降低,且差异有显著性(P<0.05);观察组术后6 h、12 h、24 h的静息视觉模拟评分(VAS)评分和运动VAS评分均低于对照组,且差异有显著性(P<0.05)。观察组镇痛满意度为75.5%(40/53),高于对照组的56.6%(30/53)(P<0.05)。观察组镇痛泵按压次数低于对照组,且差异有显著性(P<0.05)。【结论】 罗哌卡因复合右美托咪定连续股神经阻滞可增强老年全膝关节置换患者的术后镇痛效果,有效改善睡眠质量,并降低术后谵妄的发生。
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朱明霞
何花丽
关键词 关节成形术,置换,膝神经传导阻滞/方法酰胺类/治疗应用右美托咪啶/治疗应用麻醉    
Abstract【Objective】 To investigate the effect of ropivacaine combined with dexmedetomidine continuous femoral nerve block on analgesia, sleep quality and postoperative delirium in elderly patients with total knee arthroplasty. 【Methods】 A total of 106 elderly patients with total knee replacement who will be treated in our hospital from May 2016 to October 2018 were selected.The patients were randomly divided into control and observation groups by random number table method, with 53 patients in each group.All patients underwent continuous femoral nerve block under ultrasound guidance in both groups, while the control group was administered 0.2% ropivacaine 200ml and the observation group was administered 0.2% ropivacaine 200ml+ 4ug / kg dexmedetomidine.The efficacy of analgesia, quality of sleep, postoperative delirium and occurrence of postoperative complications were compared between the two groups. 【Results】 The numerical rating scale (NRS) and the delirium assessment scale in the ICU (CAM-ICU) scores on postoperative days 1, d2, and d3 were significantly lower in the observation group compared with the control group (P<0.05), and the resting visual analog scale (VAS) scores and motor VAS scores on postoperative days 6, 12, and 24 in the observation group were lower than those in the control group (P<0.05).Satisfaction with analgesia in the observation group was 75.5% (40 / 53) higher than that in the control group at 56.6% (30 / 53) (P<0.05).The number of analgesic pump compressions in the observation group was lower than that in the control group, and the difference was significant (P<0.05).【Conclusion】 Ropivacaine combined with dexmedetomidine continuous femoral nerve block enhances postoperative analgesia, effectively improves sleep quality, and reduces the occurrence of postoperative delirium in elderly patients undergoing total knee replacement.
Key wordsArthroplasty,Replacement, Knee    Nerve Block/MT    Amides/TU    Dexmedetomidine/TU    Anesthesia
收稿日期: 2019-09-20     
中图分类号:  R684.76  
通讯作者: * E-mail:2356248720@qq.com   
引用本文:   
朱明霞, 何花丽. 罗哌卡因复合右美托咪定连续股神经阻滞对老年全膝关节置换患者的效果[J]. 医学临床研究, 2021, 38(4): 553-555.
ZHU Ming-xia, HE Hua-li. Ropivacaine Compounded with Dexmedetomidine Continuous Femoral Nerve Block in Elderly Patients undergoing Total Knee Replacement. JOURNAL OF CLINICAL RESEARCH, 2021, 38(4): 553-555.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2021.04.021     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2021/V38/I4/553
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