Comparative Study of Clinical Efficacy and the Change of Inflammatory Factors Between the Solitaire Mechanical Thrombectomy and Arterial Thrombolysis in Treatment of Acute Cerebral Infarction
Abstract：【Objective】 To investigate the clinical efficacy and the change of inflammatory factors between the Solitaire mechanical thrombectomy and arterial thrombolvsis in treatment of acute cerebral infarction. 【Methods】 The clinical data of 60 patients with acute cerebral infarction treated in our hospital from June 2017 to July 2019 were analyzed retrospectively. The patients were divided into thrombolysis group (30 patients applied with the intra-arterial thrombolys) and thrombectomy group (30 patients received mechanical thrombectomy) according to the different treatment methods. The NIHSS score after the treatment, cure rate, bleeding rate, the TICI rating to assess the interventional recanalization and the change of inflammatory factors were detected. 【Results】 The NIHSS score of thrombectomy group was better than that of the thrombolysis group in a week after the treatment (P<0.05). The total effective rate reached 70.0% in the mechanical thrombectomy group and 50.0% in the arterial thrombolysis group (P<0.05). The bleeding rate was 6.7% in thrombectomy group, lower than thrombolysis group, the difference was significant (P<0.05). The recanalization rate was lower in thrombectomy group (P<0.05). The value of serum IL-6, TNF-α, hs-CRP at first, seventh and fourteenth day of treatment increased first and decreased afterward, MMP-9 showed a decreasing trend. 【Conclusion】 Compared to thrombolysis, thrombectomy can provide higher effective rate, lower bleeding rate and is beneficial to postoperative recovery.
李涛. Solitaire支架机械取栓与动脉溶栓治疗急性脑梗死的效果及对患者血清炎症因子的影响[J]. 医学临床研究, 2021, 38(4): 536-538.
LI Tao. Comparative Study of Clinical Efficacy and the Change of Inflammatory Factors Between the Solitaire Mechanical Thrombectomy and Arterial Thrombolysis in Treatment of Acute Cerebral Infarction. JOURNAL OF CLINICAL RESEARCH, 2021, 38(4): 536-538.
2021, Vol. 38 
