Abstract：【Objective】 To investigate the changes of cardiopulmonary function before and after 6 minutes walking test(6MWT) in patients with right heart dysfunction in acute exacerbation stage of chronic obstructive pulmonary disease. 【Methods】 60 patients with AECOPD were selected from January to December 2019 in the emergency department of our hospital, including 30 patients with right heart dysfunction (observation group) and 30 patients without right cardiac insufficiency (control group). The patients in both groups were treated with 6MWT, and the heart rate (HR), blood pressure (SBP), diastolic pressure (DBP), oxygen saturation (SpO2) were compared before and after 6MWT.【Results】 The 6 minutes walking distance(6MWD) of the observation group was (262.57 ± 83.74) m, which was significantly lower than that of the control group (313.60±75.33) m (t=-2.48,P=0.016). After 6MWT test, HR, SBP, DBP were significantly higher than before 6MWT test, SpO2 was significantly lower than before 6MWT test, the differences were statistically significant (P<0.05); after 6MWT test, there was no significant difference in HR, DBP, SpO2 between the two groups (P>0.05), SBP in the observation group was significantly higher than that in the control group, the difference was statistically significant (t=2.142,P=0.036). There was no significant difference in the change values (△HR, △SBP, △SpO2, △DBP) before and after 6MWT test between the two groups (P>0.05). 6MWD was positively correlated with PaO2, △ SpO2, FEV1% pre, FEV1, FEV1 / FVC (r=0.263, 0.751, 0.598, 0.336, 0.966, all P<0.05); negatively correlated with △SBP, △HR, PaCO2 (r=0.701, 0.557, 0.313, 0.665, 0.779, all P<0.05); not significantly correlated with △DBP, FVC(r=0.017, r=0.017, all P<0.05).【Conclusion】 In AECOPD patients with right ventricular dysfunction, the decline of cardiopulmonary function is more significant. 6MWT alone may not be able to better distinguish the changes of cardiopulmonary function indexes before and after exercise.
哈斯叶提·吐尔逊, 肖春红, 艾尔西丁·吾斯曼, 梁玥, 穆叶赛·尼加提, 吴长东. AECOPD合并右心功能不全患者6分钟步行试验前后心肺功能的变化*[J]. 医学临床研究, 2021, 38(4): 530-532.
Hasiyeti·Tuerxun, XIAO Chun-hong, Aierxiding·Wusiman, et al. Changes of Cardiopulmonary Function in AECOPD Patients with Right Ventricular Dysfunction Before and After 6-minute Walking Test. JOURNAL OF CLINICAL RESEARCH, 2021, 38(4): 530-532.
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2021, Vol. 38 
