Abstract：【Objective】To investigate the effect of the ultrasound guided radiofrequency ablation on benign breast nodules treatment and its influencing factors. 【Methods】A total of 62 patients with benign breast nodules (98 nodules in total) treated in our hospital from January 2016 to May 2017 were selected for the study. All patients underwent ultrasound-guided radiofrequency ablation and their clinical data were collected. Then the preoperative and postoperative values were calculated, including monthly record of focal ablation volume, lesion reduction of all focal ablation volume, and elasticity ratio of ablation lesions in the ultrasound E imaging mode. Then the correlations among the nodule size, breast physiology stages, nodal position quadrant and focal ablation volume reduction decrease were analyzed through the Pearson correlation analysis. 【Results】The postoperative focal ablation volume was decreased at 1,3,6,9 and 9 months after operation (P<0.05); The postoperative focal ablation volume reduction rate was increased accordingly, and the difference was statistically significant (P<0.05). The postoperative elasticity Ratio showed an increasing trend (P<0.05). The preoperative and postoperative elasticity Ratio was negatively correlated with preoperative and postoperative focal ablation volume (r=-3.87, P=0.026), while it was positively correlated with the postoperative focal ablation volume reduction rate (r=0.014, P=0.030). The postoperative focal ablation volume reduction rate was not correlated with the breast physiology stages and nodal position quadrant (P>0.05), but it was positively correlated with the nodule size (t=3.971, P=0.040).Nodules with a diameter of less than 1 cm and nodules with a diameter of 1 to 3 cm showed an upward trend in the reduction rate of ablation foci after operation, and the difference was statistically significant (P<0.05). Nodules with a diameter of 1 to 3 cm after the operation decreased in volume. The rate was significantly higher than that of <1 cm diameter nodules; and the difference was statistically significant (P<0.01).【Conclusion】Ultrasound-guided radiofrequency ablation in the treatment of benign breast nodules achieves a relatively better effect, which is affected by the nodule size. Moreover, the study reveals that the postoperative nodules with length of 1cm~3cm have a better prognosis.
2021, Vol. 38 
