Abstract:【Objective】 To investigate the effect of ultrasound-guided adductor block and femoral nerve block for postoperative analgesia of tibial fracture. 【Methods】 A total of 80 patients with tibial fracture in our hospital were selected and divided into observation group (n=47) and control group (n=33) according to different analgesic schemes. The control group was given ultrasound-guided femoral nerve block analgesia, and the observation group was given ultrasound-guided adductor canal block. The analgesic and sedative effect, quadriceps muscle strength and adverse reaction rate of the two groups were compared.【Results】 At 12 h, 24 h and 48 h after operation, the VAS scores of the two groups when bending the knee and at rest were lower than those at 8 h and 4 h after operation (P<0.05).There was no significant difference in VAS score between the two groups at the same time when bending the knee and at rest (P>0.05). Ramsay scores at 8 h, 12 h and 24 h after operation in the two groups were lower than those at 4 h after operation (P<0.05). There was no significant difference in Ramsay scores between the two groups at the same time (P>0.05).The muscle strength of quadriceps femoris in the control group: preoperative > 24 h after operation > 48 h after operation (P<0.05), there was no significant change in the observation group (P>0.05); the muscle strength of the observation group 24 h and 48 h after operation were greater than those of the control group (P<0.05). The incidence of adverse reactions in the observation group was 19.15% (9/47), which was significantly lower than 42.42% (14/33) in the control group, and the difference was statistically significant (χ2=5.127,P<0.05).【Conclusion】 Ultrasound guided adductor block has the same analgesic and sedative effects as femoral nerve block, but adductor block is more rapid in analgesia, has less effect on quadriceps muscle strength, and is more conducive to early postoperative rehabilitation treatment with higher safety.