外科手术治疗颅内海绵状血管瘤伴癫痫的安全性及效果观察

doi:10.3969/j.issn.1671-7171.2020.08.019

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摘要【目的】探讨外科手术治疗颅内海绵状血管瘤伴癫痫的安全性及临床效果。【方法】选取2013年1月至2017年8月本院收治的颅内海绵状血管瘤伴癫痫患者76例,记录患者术后临床效果,术后神经功能恢复情况及临床并发症发生情况。【结果】 76例患者术后随访,末次随访Engel分级:Ⅰ级41例(53.95%),Ⅱ级19例(25.00%),Ⅲ级12例(15.79%),Ⅳ级4例(5.26%),无死亡患者。病程＜2年、手术方式为完整切除+热灼的患者术后Engel评分Ⅰ级的比例分别为78.79%和65.91%,明显高于病程≥2年、手术方式为完整切除患者(P<0.05)。Logistic回归分析结果显示,病程≥2年是患者术后Engel评分Ⅰ级的危险因素(OR=1.956,P<0.05),手术方式为完整切除+热灼是患者术后Engel评分Ⅰ级的保护因素(OR=0.643,P<0.05)。【结论】外科手术治疗颅内海绵状血管瘤伴癫痫有较好的效果和安全性,值得临床推广应用。

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	郭紫康
	权天龙

关键词 ：血管瘤, 海绵状/外科学, 血管瘤, 海绵状/并发症, 脑肿瘤

Abstract：【Objective】 To investigate the safety and clinical effect of surgical treatment of intracranial cavernous hemangioma with epilepsy. 【Methods】 A total of 76 cases of intracranial cavernous hemangioma with epilepsy in our hospital from January 2013 to August 2017 were selected. The postoperative clinical effect, postoperative neurological function recovery and clinical complications were recorded.【Results】 76 patients were followed up postoperatively. At the last follow-up, Engel classification was grade Ⅰ in 41 cases (53.95%), grade Ⅱ in 19 cases (25.00%), grade Ⅲ in 12 cases (15.79%), grade Ⅳ in 4 cases (5.26%). The proportion of patients with course of disease less than 2 years and surgical method of complete resection + cauterization were 78.79% and 65.91%, respectively, which were significantly higher than those of patients with course of disease ≥ 2 years and complete resection (P<0.05).Logistic regression analysis showed that duration of disease ≥ 2 years was the risk factor of Engel grade Ⅰ (OR=1.956, P<0.05).Complete resection + cauterization were the protective factors of Engel grade Ⅰ (OR=0.643, P<0.05).【Conclusion】 Surgical treatment of intracranial cavernous hemangioma with epilepsy has good effect and safety, worthy of clinical application.

Key words： Hemangioma, Cavernous/SU Hemangioma, Cavernous/CO Brain Neoplasms

收稿日期: 2018-10-10

PACS:

R732.2

通讯作者: E-mail:qtl19771202@sina.cn

引用本文:

郭紫康, 权天龙. 外科手术治疗颅内海绵状血管瘤伴癫痫的安全性及效果观察[J]. 医学临床研究, 2020, 37(8): 1181-1183.
GUO Zi-kang, QUAN Tian-long. Safety and Efficacy of Surgical Treatment of Intracranial Cavernous Hemangioma with Epilepsy. JOURNAL OF CLINICAL RESEARCH, 2020, 37(8): 1181-1183.

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