Abstract：【Objective】To explore the clinical value of thromboelastography (TEG) in the evaluation of patients with unstable angina pectoris (UAP) and antiplatelet therapy after PCI.【Methods】One hundred and seventeen UAP patients in our hospital were divided into single vessel disease, double vessel disease and three vessel disease groups according to the number of coronary lesions. TEG parameters of each group were compared. According to the different antiplatelet treatment methods of UAP patients after PCI, they were divided into clopidogrel group and tegrerolol group. The platelet inhibition rate and TEG parameters of the two groups were analyzed.【Results】The response time (R) of UAP patients in the three vessel disease group and the two vessel disease group was significantly lower than that the in single vessel the disease group, and the R value of UAP patients in the three vessel disease group was significantly lower than that in the two vessel disease group; the α angle and Ma value of UAP patients in the three vessel disease group and the two vessel disease group were significantly higher than that in the single vessel disease group, and the α angle and Ma value of UAP patients in the three vessel disease group were significantly higher than that in the two vessel disease group (P<0.05). After PCI, the R value of the tegrilol group was higher than that of the clopidogrel group, while the α angle and MA value were lower than those of the clopidogrel group (P<0.05). After PCI, the platelet inhibition rate of AA pathway and ADP pathway in the tegrilol group was higher than that in the clopidogrel group (P<0.05).【Conclusion】TEG detection has a certain clinical value in evaluating the degree of coronary lesions in UAP patients and the effect of antiplatelet therapy after PCI.
吴炎, 江礼娟, 王亚年, 蒲红. 血栓弹力图在不稳定心绞痛患者病情评估及PCI术后抗血小板治疗中的临床价值[J]. 医学临床研究, 2020, 37(2): 249-251.
WU Yan, JIANG Li-juan, WANG Ya-nian,et al. Clinical Value of Thromboelastography(TEG) in the Evaluation of Patients with Unstable Angina and Antiplatelet Therapy after PCI. JOURNAL OF CLINICAL RESEARCH, 2020, 37(2): 249-251.
2020, Vol. 37 
