动脉置管溶栓结合Angiojet血栓抽吸系统治疗下肢动脉血栓疗效观察

doi:10.3969/j.issn.1671-7171.2020.01.021

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摘要 【目的】 探讨动脉置管溶栓(CDT)结合Angiojet血栓抽吸系统治疗下肢动脉血栓患者疗效。【方法】 选择60例下肢动脉血栓患者,根据随机数表法将其分为观察组和对照组,每组30例。对照组患者行CDT治疗,观察组患者行Angiojet血栓抽吸系统结合CDT治疗。比较两组患者的治疗效果、围手术期指标、踝肱指数(ABI)、截肢率、尿激酶使用量以及导管留置时间、SF-36评分之间的差异。【结果】 观察组患者临床优良率83.33%(25/30)高于对照组的60.00%(18/30),差异有统计学意义(χ²=4.023,P<0.05)。两组患者SBP、PaO₂、SpO₂水平高于治疗前,且观察组SBP水平低于对照组,PaO₂、SpO₂高于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者的ABI显著升高,且观察组患者的ABI显著高于对照组,截肢率显著低于对照组 ,观察组患者尿激酶使用量及导管留置时间均显著低于对照组(P<0.05)。观察组患者生理功能、社会功能、生理职能、活力、情感职能、精神健康、躯体疼痛与总体健康评分均显著高于对照组,差异有统计学意义(P<0.05)。【结论】 CDT结合Angiojet血栓抽吸系统治疗下肢动脉血栓患者可升高ABI指数,降低截肢率,患者疗效显著,值得临床推广应用。

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	曾光
	黄毅
	黄荣
	李梦帆

关键词 ：下肢/血液供给, 血栓形成, 动脉

Abstract：【Objective】To explore the effect of CDT combined with Angiojet thrombus extraction system on lower extremity arterial thrombosis, ankle brachial index (ABI) and amputation rate.【Methods】From January 2018 to June 2019, 60 patients with lower extremity arterial thrombosis were selected and divided into observation group and control group according to the random number table method, 30 in each group. The patients in the control group were treated with CDT, and the patients in the observation group were treated with Angiojet thrombus aspiration system combined with CDT. The therapeutic effect, perioperative index, ABI, amputation rate, urokinase usage, catheter retention time and SF-36 score of the two groups were compared. 【Results】The clinical excellent and good rate of the observation group was 83.33% (25 / 30) higher than that of the control group (60.00% (18 / 30), the difference was statistically significant (χ² = 4.023, P<0.05). The SBP, PaO₂ and SpO₂ levels of the two groups were higher than those before treatment, and the SBP level of the observation group was lower than that of the control group, and the PaO₂ and SpO₂ levels of the observation group were higher than that of the control group, the difference was statistically significant (P<0.05). After treatment, the ABI of the two groups increased significantly, and the ABI of the observation group was significantly higher than that of the control group, the amputation rate was significantly lower than that of the control group, and the use of urokinase and catheter retention time of the observation group were significantly lower than that of the control group (P<0.05). The scores of physiological function, social function, physiological function, vitality, emotional function, mental health, physical pain and general health in the observation group were significantly higher than those in the control group (P<0.05).【Conclusion】CDT combined with Angiojet thrombus extraction system can increase the ABI index and reduce the amputation rate in patients with lower extremity arterial thrombus, which is worth clinical application.

Key words： Lower Extremity/BS Thrombosis Arteries

收稿日期: 2019-10-15

PACS:

R543.5

基金资助:上海市普陀区中心医院科研项目(编号:2017306A)

引用本文:

曾光, 黄毅, 黄荣, 李梦帆. 动脉置管溶栓结合Angiojet血栓抽吸系统治疗下肢动脉血栓疗效观察[J]. 医学临床研究, 2020, 37(1): 68-70.
ZENG Guang, HUANG Yi, HUANG Rong,et al. Treatment of Lower Extremity Arterial Thrombus with Arterial Catheterization and Thrombolysis Combined with Angiojet Thrombus Extraction System. JOURNAL OF CLINICAL RESEARCH, 2020, 37(1): 68-70.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.01.021 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I1/68

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