Abstract：【Objective】To explore the diagnostic value of American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS) classification combined with contrast-enhanced ultrasound (CEUS) for benign and malignant thyroid nodules. 【Methods】The sonographic images and CEUS imaging data of 105 patients with thyroid nodules (153 nodules in total) were retrospectively analyzed. All thyroid nodules were classified into corresponding categories according to the criteria of ACR TI-RADS (version of year 2017). The diagnostic value of ACR TI-RADS classification combined with CEUS in benign and malignant thyroid nodules was evaluated based on the results of final surgical pathology examination. 【Results】The pathological results showed that there were 94 benign nodules and 59 malignant nodules among total 153 thyroid nodules. The sensitivity, specificity, accuracy, positive and negative predictive value of ACR TI-RADS combined with CEUS for thyroid cancer diagnosis were 93.22%,95.74%,94.77%,93.22%,and 95.74%, respectively, which were significantly higher than those of either ACR TI-RADS alone (71.19%,84.04%,79.08%,73.68% and 82.29%, respectively,) or CEUS alone (79.66%,86.17%,83.66%,78.33% and 87.1%, respectively). The differences were statistically significant (all P<0.05). 【Conclusion】The ACR TI-RADS classification combined with CEUS has a high diagnosis value for benign and malignant thyroid nodules. It is worthy of clinical application.
[1] 黄雪,夏红梅,谭开彬,等.超声及诊断甲状腺良恶性结节的临床研究[J].中国CT和MRI杂志, 2017, 15(2):39-41. [2] 詹维伟, 徐上妍.甲状腺结节超声检查新进展[J].中华医学超声杂志电子版, 2013, 10(2):88-93. [3] Tessler FN, Middleton WD, Grant EG,et al.ACR thyroid imaging reporting and data system (TI-RADS): white paper of the ACR TI-RADS committee[J].J Am Coll Radiol,2017, 14(5):587-595. [4] Wendl CM,Janke M,Jung W,et al.Contrast-enhanced ultrasound with perfusion analysis for the identification of malignant and benign tumours of the thyroid gland[J].Clin Hemorheol Microcirc,2015, 63(2):113-121. [5] Zhang Y, Luo YK, Zhang MB, et al.Diagnostic accuracy of contrast-enhanced ultrasound enhancement patterns for thyroid nodules[J].Med Sci Monit,2016, 22:4755-4764. [6] 中华医学会内分泌学分会.甲状腺结节和分化型甲状腺癌诊治指南[J].中国肿瘤临床, 2012, 33(17):779-797. [7] Middleton WD, Teefey SA, Reading C, et al.Multi-institutional analysis of thyroid nodule risk stratification using the American College of Radiology Thyroid Imaging,Reporting and Data System[J].Am J Roentgenol,2017, 208(6):1324-1334. [8] 刘红, 胡正明, 罗海愉,等.分类在诊断甲状腺结节中的应用价值探究[J].中国超声医学杂志, 2018, 34(8):673-674. [9] Zhang B, Jiang YX, Liu JB, et al.Utility of contrast enhanced ultrasound for evaluation of thyroid nodules[J].Thyroid,2010, 20(1):51-57. [10] 王潇婧, 刘利平.分类与年指南对甲状腺结节诊断价值的比较研究[J].中华临床医师杂志电子版, 2018, 12(4):223-226. [11] 邬亮, 姚树新, 何东方.甲状腺影像报告和数据系统联合超声弹性成像对甲状腺良恶性结节的诊断价值[J].中国临床医学影像杂志, 2018, 29(5):309-312. [12] Lee JH,Shin HJ,Yoon JH,et al.Predicting lymph node metastasis in patients with papillary thyroid carcinoma by vascular index on power doppler ultrasound[J].Head Neck,2017, 39(2):334-340. [13] Yu D,Han Y, Chen T.Contrast-enhanced ultrasound for differentiation of benign and malignant thyroid lesions:Meta-analysis[J].Otolaryngol Head Neck Surg,2014, 151(6):909-915.
2019, Vol. 36 
