Early Respiratory Function Exercise Combined with Nasal High Flow Oxygen Therapy on Rehabilitation and Pulmonary Function in Children with Tetralogy of Fallot
Abstract：【Objective】To explore the effect of early respiratory function training combined with nasal high flow oxygen therapy on the rehabilitation and pulmonary function of children with tetralogy of Fallot (TOF). 【Methods】Eighty-seven children with TOF admitted to our hospital from March 2016 to March 2018 were randomly divided into observation group (n=44) and control group (n=43) according to random number table method. The observation group was treated with early respiratory function exercise combined with nasal high flow oxygen therapy, while the control group was treated with nasal high flow oxygen therapy. The two groups were treated for one month. The changes of SGRQ, blood gas analysis index and pulmonary function before and after treatment were compared between the two groups. 【Results】After treatment, the SGRQ score of the two groups decreased, and the SGRQ score of the observation group was lower than that of the control group (P<0.05). After treatment, the arterial partial pressure of oxygen (PaO2), pH value, pulse oxygen saturation(SpO2 ) increased and the arterial partial pressure of carbon dioxide (PaCO2) decreased in both groups. The PaO2, pH value and SpO2 value in the observation group were higher than those in the control group, and the PaCO2 level was lower than that in the control group (P<0.05). After treatment, the percentage of vital capacity (VC), forced expiratory volume (FEV1), forced vital capacity (FVC), forced expiratory volume (FEV1), forced expiratory volume (FVC), forced expiratory volume (FEV1/FVC) of the two groups increased, and the values of VC, FEV1, FVC and FEV1/FVC of the observation group were higher than those of the control group (P<0.05). 【Conclusion】Early respiratory function exercise combined with nasal high flow oxygen therapy for TOF can effectively improve the quality of life, shorten hospitalization time, improve the blood gas index and pulmonary function of children with TOF, and has high safety.
杨贵红, 肖剑锋, 罗金文, 田甫翠, 李运飞, 张凯. 早期呼吸功能锻练联合经鼻高流量氧疗对法洛四联症手术患儿康复及肺功能的影响[J]. 医学临床研究, 2019, 36(9): 1709-1711.
YANG Gui-hong, XIAO Jian-feng, LUO Jin-wen,et al. Early Respiratory Function Exercise Combined with Nasal High Flow Oxygen Therapy on Rehabilitation and Pulmonary Function in Children with Tetralogy of Fallot. JOURNAL OF CLINICAL RESEARCH, 2019, 36(9): 1709-1711.
2019, Vol. 36 
