Abstract：【Objective】To investigate ultrasound bone mineral density (BMD), serum calcium level and body mass index (BMI) in preeclampsia pregnant women. 【Methods】We selected 50 preeclampsia pregnant women from January 2017 to December 2017 as the observation group and 50 healthy pregnant women in our hospital during the same period as the control group. All patients underwent ultrasound bone mineral density (BMD) detection. According to the T value of the bone density of the pregnant women, the pregnant women in the observation group were divided into the normal bone group, the osteopenia group and the osteoporosis group. The bone mineral status, serum calcium, serum iron and body mass index (BMI) of the two groups were measured. Pearson correlation analysis was used to observe the correlation of BMD with serum calcium and body mass index. Logistic regression analysis of factors affecting the T value of bone mineral density in preeclampsia.【Results】The proportion of pregnant women with normal bone in the observation group was 28.00%, which was significantly lower than 76.00% in the control group, while the proportion of pregnant women with osteopenia and osteoporosis was significantly higher than that in the control group. There was no significant difference in the early pregnancy blood calcium and iron, and blood iron in late pregnancy between the two groups (P>0.05). The blood calcium in the late pregnancy and the BMI in the early pregnancy were both significantly lower than those in the control group. Correlation analysis showed that the bone density T value in the observation group was positively correlated with serum calcium concentration and BMI in early pregnancy. There were no significant differences in the age, height, early pregnancy weight, gestational age, pregnancy, birth, and gestational diabetes mellitus among the normal bone group, the osteopenia group and the osteoporosis group (P>0.05). However, there were significant differences in daily activity time, calcium supplement, vitamin supplement and calcium + vitamin supplement among the three groups (P<0.05). Multivariate logistic regression analysis showed that daily activity, vitamin supplementation, vitamin supplement and calcium plus vitamin supplementation were the factors influencing bone mineral density in pregnant women. 【Conclusion】Bone mineral density, serum calcium and body mass index are closely related during pregnancy. The change of bone mineral density can provide reference for the diagnosis of preeclampsia. Increasing daily activity time, calcium supplementation and vitamin supplementation can improve the bone mineral density of pregnant women, thereby reducing the risk of bone calcium loss leading to preeclampsia.
王妍, 唐桂娥, 陶彩霞. 子痫前期孕妇骨密度的影响因素分析[J]. 医学临床研究, 2019, 36(8): 1525-1527.
WANG Yan, TANG Gui-e, TAO Cai-xia. Influencing Factors of Bone Mineral Density in Preeclampsia Pregnant Women. JOURNAL OF CLINICAL RESEARCH, 2019, 36(8): 1525-1527.
2019, Vol. 36 
