医学临床研究
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医学临床研究  2019, Vol. 36 Issue (5): 888-890    DOI: 10.3969/j.issn.1671-7171.2019.05.018
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咪达唑仑联合瑞芬太尼在脊椎骨折手术中的麻醉效果及对血流动力学的影响
刘星1, 邱德亮2, , 王左峰1, 欧珊1
1.成都市第一人民医院麻醉科,四川 成都 610000;
2.成都市龙泉驿区第一人民医院麻醉科,四川 成都 610100
Effect of Midazolam Combined with Remifentanil on Anesthesia and Hemodynamics in Spinal Fracture Surgery
LIU Xing, QIU De-liang, WANG Zuo-feng, et al
Department of Anestheisology, Chengdu First People's Hospital, Sichuan Chengdu,610000
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摘要 【目的】探讨咪达唑仑联合瑞芬太尼在脊椎骨折手术中的麻醉效果及对患者血流动力学的影响。【方法】选择2016年6月至2018年2月在本院诊治的脊椎骨折患者84例,按照随机数表法分为对照组和观察组,每组42例。对照组给予咪达唑仑注射液麻醉,观察组在对照组基础上加用瑞芬太尼麻醉,比较两组患者麻醉效果、血流动力学及麻醉并发症发生率。【结果】观察组麻醉后呼吸恢复、睁眼、定向恢复、拔管时间及术后疼痛评分,均短(低)于对照组(P<0.05);观察组拔管时(T1)及拔管后5 min(T2)心率、平均动脉压,均显著低于对照组(P<0.05);两组麻醉后呼吸抑制、躁动、头晕头痛、共济失调、嗜睡发生率比较差异均无统计学意义(P>0.05)。【结论】咪达唑仑联合瑞芬太尼用于脊椎骨折麻醉好,患者血流动力学相对稳定,安全性较高,值得临床推广应用。
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关键词 脊柱骨折/治疗麻醉药    
Abstract【Objective】To investigate the effect of midazolam combined with remifentanil on anesthesia and hemodynamics in patients with spinal fractures. 【Methods】 Eighty-four patients with vertebral fracture treated in our hospital from June 2016 to February 2018 were divided into control group and observation group according to random number table method, 42 cases in each group. The control group was anesthetized with midazolam injection, while the observation group was anesthetized with remifentanil on the basis of the control group. The anesthetic effect, hemodynamics and incidence of anesthetic complications were compared between the two groups.【Results】 Respiratory recovery, eye opening, directional recovery, extubation time and postoperative pain scores in the observation group were shorter than those in the control group (P<0.05); heart rate and mean arterial pressure at extubation time (T1) and 5 min (T2) were significantly lower than those in the control group (P<0.05); the incidence of respiratory depression, restlessness, dizziness, headache, ataxia and sleepiness after anesthesia in the observation group were significantly lower than those in the control group (P<0.05). There was no statistical significance (P>0.05). 【Conclusion】 Midazolam injection combined with remifentanil for patients with spinal fracture can obtain good anesthetic effect, hemodynamics is relatively stable, and anesthesia safety is high, which is worthy of popularization and application.
Key wordsSpinal Fractures/TH    Anesthetics
收稿日期: 2019-02-27     
PACS:  R681.5  
通讯作者: 邮箱:313577313@qq.com   
引用本文:   
刘星, 邱德亮, , 王左峰, 欧珊. 咪达唑仑联合瑞芬太尼在脊椎骨折手术中的麻醉效果及对血流动力学的影响[J]. 医学临床研究, 2019, 36(5): 888-890.
LIU Xing, QIU De-liang, WANG Zuo-feng, et al. Effect of Midazolam Combined with Remifentanil on Anesthesia and Hemodynamics in Spinal Fracture Surgery. JOURNAL OF CLINICAL RESEARCH, 2019, 36(5): 888-890.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2019.05.018     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2019/V36/I5/888
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