摘要【目的】 探讨静吸复合麻醉与单纯静脉麻醉对腹腔镜下行宫颈癌切除术老年患者的认知功能的影响。【方法】 80例行宫颈癌切除术老年患者,按照抽签法分为两组,每组各40例,对照组采用单纯静脉麻醉,观察组采用静吸复合麻醉。比较两组患者中枢神经特异蛋白(S100β)、神经元特异性烯醇化酶(NSE)水平,简易智能精神状态量表(MMSE)、视觉模拟评分法(VAS)评分、术后认知功能障碍(POCD)发生率及不良反应发生情况。【结果】 观察组S100β、NSE水平在术后12 h、术后72 h 均显著低于对照组(P＜0.05);术后72 h MMSE评分高于、VAS评分显著低于对照组(P＜0.05),POCD及不良反应总发生率均显著低于对照组(P＜0.05)。【结论】 静吸复合麻醉与单纯静脉麻醉是腹腔镜下行宫颈癌切除术的重要麻醉方式,静吸复合麻醉具有更佳的麻醉效果,不良反应较少,可减轻患者呼吸抑制,对POCD的影响较小,有利于预后。
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2018, Vol. 35 
