Abstract：【Objective】To explore the correlation between body fat distribution and blood lipid metabolism in patients with coronary heart disease. 【Methods】A total of 70 coronary heart disease patients (the observation group) and 80 healthy volunteers ( the control group ) from June 2015 to June 2017 were enrolled in this study. Body fat composition and bone mineral density (BMD) were measured by dual-energy X-ray absorptiometry (DEXA). The levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and uric acid (UA) were compared between the two groups. The correlation between body fat distribution and lipid metabolism was analyzed in the coronary heart disease group. 【Results】There was no significant difference in age and BMI between the observation group and the control group (P>0.05). The levels of serum TG, TC, LDL-C and UA in the observation group were significantly higher than those in the control group (P<0.05), but the serum HDL-C levels were not significantly different (P>0.05). There was no significant difference in height and body weight between the observation group and the control group (P>0.05). The waist circumference, SBP and DBP in the observation group were significantly higher than the control group (P<0.05). The fat mass of the observation group was significantly higher than that of the control group, while the muscle mass, BMC and BMD were significantly lower than those of the control group (P<0.05). BMD and BMC were positively correlated with overall muscle mass, total fat mass, TG, TC and LDL-C (P<0.05).【Conclusion】Coronary heart disease has significant regression with fat mass, muscle mass, BMC and BMD, suggesting that body composition distribution and dyslipidemia play an important role in the occurrence and development of coronary heart disease.
焦巳彧, 崔玉杰, 纪美晶, 蒋韬, 毛曼, 李群, 陆强. 冠心病患者体脂分布与血脂代谢的相关性分析[J]. 医学临床研究, 2018, 35(11): 2101-2103.
JIAO Si-yu, CUI Yu-jie, JI Mei-jing, et al. Correlation between Body Fat Distribution and Blood Lipid Metabolism in Patients with Coronary Heart Disease. JOURNAL OF CLINICAL RESEARCH, 2018, 35(11): 2101-2103.
[1] 李志明.冠心病患者阿司匹林抵抗与复发心血管事件的发生及相关危险因素分析[J].医学临床研究,2016,33(1):131-132.
[2] 杨猛,朱长真,于健春,等.人体成分测量方法及其临床应用[J].中华临床营养杂志,2015,23(2):125-127.
[3] 闰丹,阮祥燕.人体成分测定方法的临床应用与进展[J].中国组织工程研究与临床康复,2011,15(24):4499-4502.
[4] Craig P,Halacatau HV,Conitoo E,et al. Differences in body composition between Tongans and Australians:time to rethink the healthy weight ranges[J]？Int J Obes Relat Metab Disord,2001,25(12):1806-1814.
[5] 严孙杰,冯霖,沈喜妹,等.健康成人体成分差异对不同年龄段人群骨密度的影响[J].福建医科大学学报,2009,43(4):301-305.
[6] 白瑾,赵威,徐昕晔,等.冠心病患者体成分与运动能力的相关性[J].北京大学学报(医学版),2014,46(6):854-856.
[7] Skrzek A, Kozie S,Ignasiak Z.The optimal value of BMI for the lowest risk of osteoporosis in postmenopausal women aged 40-88 years[J].HOMO,2014,65(3):232-239.
[8] 叶爱玲,张红,彭依群,等.体成分对不同糖耐量水平男性骨密度的影响[J].中南大学学报(医学版),2010,35(5):529-533.
[9] 黄淑玉,重远,管晓峰. 体成分对男性2型糖尿病患者骨密度的影响[J].中国骨质疏松杂志,2015,21(2):203-206.
[10] Kataoka Y,Shao M,Wolski K,et al.Multiple risk factor intervention and progression of coronary atherosclerosis in patients with type 2 diabetes mellitus[J].Eur J Prevent Cardiol,2013,20(2):209-217.
[11] 韩全乐,毛瑞英,王金艳,等.早发冠心病患者血清骨保护素水平及其临床危险因素[J].中华老年学杂志,2015,35(19):5461-5462.
2018, Vol. 35 
