Clinical Significance of Cardiac Color Doppler Ultrasound Parameters Combined with Serum Metrnl Level in Evaluating Cardiac Function and Condition of Patients with Heart Failure
ZHANG Yueyue, QIAN Yijun, Ni Ye, et al
Department of Cardiology, Kongjiang Hospital, Yangpu District, Shanghai 200093
Abstract：【Objective】To explore the clinical significance of cardiac color Doppler ultrasound parameters combined with serum meteorin-like protein (Metrnl) level in evaluating cardiac function and condition of patients with heart failure. 【Methods】A total of 120 patients with heart failure (the observation group) admitted to our hospital from October 2021 to October 2024 were selected. According to the New York Heart Association (NYHA) cardiac function classification, the observation group was divided into grade Ⅱ group (n=62) and grade Ⅲ+Ⅳ group (n=58). In addition, 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The cardiac color Doppler ultrasound parameters and serum Metrnl levels of different groups were compared, and the receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of cardiac color Doppler ultrasound parameters and serum Metrnl level for cardiac function and condition of patients with heart failure. 【Results】The left ventricular ejection fraction (LVEF) and serum Metrnl level in the observation group were lower than those in the control group, while the left atrial diameter (LAD) and left ventricular end-diastolic diameter (LVEDD) were higher than those in the control group, with statistically significant differences (P<0.05). The LVEF and serum Metrnl level in the grade Ⅱ group were higher than those in the grade Ⅲ+Ⅳ group, while the LAD and LVEDD were lower than those in the grade Ⅲ+Ⅳ group, with statistically significant differences (P<0.05). ROC curve results showed that the area under the curve (AUC) of the combination of LVEF, LAD, LVEDD and Metrnl in predicting cardiac function of patients with heart failure was significantly better than that of each index alone (P<0.05). 【Conclusion】Cardiac color Doppler ultrasound parameters combined with serum Metrnl level have good clinical application value in evaluating cardiac function and condition of patients with heart failure.
张越月, 钱一君, 倪烨, 赵娅. 心脏彩超参数联合血清Metrnl水平评估心力衰竭患者心功能及病情的临床价值[J]. 医学临床研究, 2025, 42(10): 1774-1776.
ZHANG Yueyue, QIAN Yijun, Ni Ye, et al. Clinical Significance of Cardiac Color Doppler Ultrasound Parameters Combined with Serum Metrnl Level in Evaluating Cardiac Function and Condition of Patients with Heart Failure. JOURNAL OF CLINICAL RESEARCH, 2025, 42(10): 1774-1776.
2025, Vol. 42 
