Abstract：【Objective】To explore the correlation between the level of urinary protein and the level of blood sugar and lipid in elderly patients with diabetes. 【Methods】 The clinical data of 88 elderly patients with diabetes diagnosed and treated in our hospital from June 2020 to June 2022 were retrospectively analyzed. The patients were divided into proteinuria group(n=46) and normal group(n=42) according to their urinary protein level. The general information,blood glucose and blood lipid levels of the two groups were compared. The ROC curve was used to analyze the predictive value of blood glucose and lipid levels on proteinuria in elderly patients with diabetes; Multivariate logistic regression was used to analyze the risk factors of proteinuria in elderly patients with diabetes.【Results】 The proportion of patients with body mass index(BMI) ≥ 24 kg/m2,duration of diabetes ≥ 5 years,hypertension,coronary heart disease,fasting blood glucose(FPG),glycosylated hemoglobin(HbA1c),triglyceride(TG),and total cholesterol(TC) in the proteinuria group were significantly higher than those in the normal group(P<0.05);ROC curve analysis showed that the area under the curve of FPG,HbA1c,TG and TC predicting proteinuria in elderly diabetes patients was 0.841,0.834,0.797 and 0.717,respectively; Multivariate logistic regression analysis showed that BMI ≥ 24 kg/m2,diabetes duration ≥ 5 years,hypertension,coronary heart disease,FPG ≥ 8.640 mmol/L,HbA1c ≥ 7.475%,TG ≥ 1.365 mmol/L,TC ≥ 4.870 mmol/L were risk factors for proteinuria in elderly diabetes patients(P<0.05). 【Conclusion】The level of urinary protein in elderly patients with diabetes is related to the level of blood sugar and blood lipid,and the level of hyperglycemia and blood lipid is related to diabetes nephropathy.
张彦清, 樊星涛, 任伟娟. 尿蛋白水平与老年糖尿病患者血糖、血脂水平的相关性分析[J]. 医学临床研究, 2023, 40(11): 1670-1672.
ZHANG Yanqing, FAN Xingtao, REN Weijuan. Correlation between Urinary Protein Level and Blood Glucose and Lipid Levels in Elderly Patients with Diabetes. JOURNAL OF CLINICAL RESEARCH, 2023, 40(11): 1670-1672.
2023, Vol. 40 
