Abstract：Objective To explore the effect of dexmedetomidine combined with comfort counseling on restlessness during recovery period of general anesthesia in children, and to analyze its clinical application value. Methods One hundred and fifty-four cases of adenoidectomy under general anesthesia in our hospital from March 2016 to June 2018 were selected for prospective control study. The children were divided into dexmedetomidine group, combination group and control group by random number table method, 51 cases in each group. After tracheal intubation, dexmedetomidine group and combination group were given dexmedetomidine pump injection (the control group was pumped with the same amount of saline). The combination group was given comfortable counseling before operation. The changes of physiological state, Ramsay sedation score 1-4 hours after extubation, recovery time, restlessness score and number of restlessness cases were compared among the three groups. The anesthetic effect and safety of different schemes and their effects on restlessness during the recovery period of general anesthesia were analyzed. Results Heart rate (HR) decreased 10 to 60 minutes after awakening in all three groups. HR in the dexmedetomidine group was lower than that in the control group, and HR in the combination group was lower than that in the dexmedetomidine group (P<0.05). Ramsay scores of the three groups at 2~4 hours after extubation were higher than those at 1 hour after extubation. Ramsay scores of the dexmedetomidine group at 1 h, 2 h and 4 h after extubation were higher than those of the control group. Ramsay scores of the combined group at 1 h, 2 h, 3 h and 4 h after extubation were higher than those of the dexmedetomidine group, with statistical significance (P<0.05). The restlessness score of the control group was lower than that of the dexmedetomidine group, and the restlessness score of the dexmedetomidine group was lower than that of the combination group (F=5.879,P=0.000). The incidence of restlessness in the control group was 29.41% (15/51) higher than that in the dexmedetomidine group 15.69% (8/51), and that in the dexmedetomidine group was 3.92% (2/51) higher than that in the combination group (χ2 = 3.015,P=0.013).Conclusion Dexmedetomidine can effectively prevent restlessness during the recovery period of general anesthesia in children without affecting the safety of anesthesia. On this basis, combined comfort counseling can further improve the preventive effect of restlessness.
张元歌, 毛红平. 右美托咪定联合舒适性疏导对小儿全麻苏醒期躁动的影响[J]. 医学临床研究, 2019, 36(2): 230-232.
ZHANG Yuan-ge, MAO Hong-ping. Effect of Dexmedetomidine Combined with Comfort Counseling on Restlessness During Recovery from General Anesthesia in Children. JOURNAL OF CLINICAL RESEARCH, 2019, 36(2): 230-232.
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2019, Vol. 36 
