Clinical Analysis of Thrombolysis before Transportation for PCI in Patients with Acute ST Segment Elevation Myocardial Infarction Complicated with Pulmonary Infection
LI Zhe, MING Hui, LI Feng-jie
Beijing Luhe Hospital, Capital Medical University, Beijing 101100
Abstract：【Objective】To investigate the clinical effect of thrombolysis before transporting for PCI in patients with STEMI complicated with pulmonary infection. 【Methods】From January 2016 to December 2018, 200 patients with STEMI and pulmonary infection who were treated by PCI were divided into observation group (n=76, thrombolysis before transport) and control group (n=124, none thrombolysis before transport) according to whether thrombolysis was performed before referral. The changes of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESD) were observed. The serum levels of procalcitonin (PCT) and C-reactive protein (CRP) were compared before and 7 days after treatment. The patients were followed up for half a year to observe the adverse events of the two groups. 【Results】After treatment, LVEDD and LVESD of the two groups were lower than before treatment, and LVEF was higher than before treatment. LVEDd and LVESD of the observation group were lower than that of the control group, and LVEF was higher than that of the control group, the difference was statistically significant (P<0.05). After treatment, the levels of PCT and CRP in serum of the two groups were lower than that before treatment, and that in the observation group was lower than that in the control group (P<0.05). After 6 months follow-up, the incidence of cardiovascular adverse events in the observation group was 5.26% (4 / 76) lower than that in the control group (14.52%) (18/124), the difference was statistically significant (χ2=4.121,P=0.042<0.05). 【Conclusion】Thrombolysis before transportation for PCI is helpful for the recovery of heart function and the control of pulmonary infection in patients with STEMI complicated with pulmonary infection, and it can reduce the risk of cardiovascular adverse events, which is worthy of clinical reference.
李哲, 明辉, 李凤杰. 急性ST段抬高心肌梗死合并肺部感染患者溶栓后转运行PCI临床效果分析[J]. 医学临床研究, 2019, 36(12): 2302-2304.
LI Zhe, MING Hui, LI Feng-jie. Clinical Analysis of Thrombolysis before Transportation for PCI in Patients with Acute ST Segment Elevation Myocardial Infarction Complicated with Pulmonary Infection. JOURNAL OF CLINICAL RESEARCH, 2019, 36(12): 2302-2304.
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2019, Vol. 36 
