Abstract【Objective】 To investigate the value of erythrocyte distribution width (RDW) and ratio of RDW/serum calcium in evaluating the condition and prognosis of patients with acute pancreatitis. 【Methods】 A total of 153 patients with AP in our hospital were selected as the research subjects. The clinical data of all patients were analyzed and the risk factors affecting the severity and poor prognosis of AP patients were analyzed. The value of RDW and ratio of RDW/serum calcium in evaluating the condition and prognosis of AP patients was explored. 【Results】 Univariate and logistic regression analysis showed that the AP patients with RDW>15.56%, BUN>23.52 mg/dL and ratio of RDW / serum calcium>1.79 were more severe. The AUC of AP patients diagnosed by the ratio of RDW / serum calcium was greater than that of AP patients diagnosed by RDW and BUN, but the difference was not statistically significant (P>0.05).Univariate and logistic regression analysis also showed that the prognosis of AP patients with RDW>15.56%, APACHE Ⅱ>14.06, lactate >2.40mg/dL and ratio of RDW / serum calcium>1.79 was worse. The prognosis of AUC in patients with AP diagnosed by RDW/serum calcium was lower than that of APACHE Ⅱ, while it was higher than that of RDW and lactic acid, but the differences were not statistically significant (P>0.05). 【Conclusion】 RDW/ serum calcium is an independent influence factor of AP patients' worsening condition and poor prognosis. RDW/ serum calcium can be used as a reference index for evaluating the condition and prognosis of AP patients.
YIN Yang,ZHANG Rui. Value of Erythrocyte Distribution Width and Serum Calcium Ratio in Evaluating the Condition and Prognosis of Patients with Acute Pancreatitis[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(4): 526-529.
[1] DURMAZ M S, ARSLAN S. Effectiveness of shear wave elastography in the diagnosis of acute pancreatitis on admission[J].Med Ultrason,2018,20(3):278-284.
[2] SONG J, ZHONG Y, LU X, et al. Enteral nutrition provided within 48 hours after admission in severe acute pancreatitis: A systematic review and meta-analysis[J].Medicine (Baltimore),2018,97(34):e11871.
[3] 郑丹,张胜,崔可,等.平均血小板体积联合红细胞分布宽度对重症急性胰腺炎预后的价值[J].实用医学杂志,2018,34(8):1294-1300.
[4] 卢清龙,赵萍,马增香,等.红细胞分布宽度对急性胰腺炎严重程度及预后判断的价值[J].山东医药,2015,55(13):46-47.
[5] 中华医学会外科学分会胰腺外科学组.急性胰腺炎诊治指南(2014版)[J].中华消化外科杂志,2015,14(1):1-5.
[6] 陈玲.Ranson、CTSI和BISAP评分在判断急性胰腺炎病情和预后中的意义[J].中华胰腺病杂志,2016,16(4):261-264.
[7] 孙喜斌,张玉虹,贾倩,等.上消化道出血患者红细胞分布宽度变化及意义[J].山东医药,2018,58(5):40-42.
[8] PANG Y, KARTSONAKI C, TURNBULL I, et al. Metabolic and lifestyle risk factors for acute pancreatitis in Chinese adults: a prospective cohort study of 0.5 million people[J].PLoS Med,2018,15(8):e1002618.
[9] YALÇIN M S, TAS A, KARA B, et al. New predictor of acute necrotizing pancreatitis: red cell distribution width[J].Adv Clin Exp Med,2018,27(2):225-228.
[10] YE J F, ZHAO Y X, JU J, et al. Building and verifying a severity prediction model of acute pancreatitis (AP) based on BISAP, MEWS and routine test indexes[J].Clin Res Hepatol Gastroenterol,2017,41(5):585-591.
[11] GRAVITO-SOARES M, GRAVITO-SOARES E, GOMES D, et al. Red cell distribution width and red cell distribution width to total serum calcium ratio as major predictors of severity and mortality in acute pancreatitis[J].BMC Gastroenterol,2018,18(1):108.
[12] GOYAL H, AWAD H, HU Z D. Prognostic value of admission red blood cell distribution width in acute pancreatitis: a systematic review[J].Ann Transl Med,2017,5(17):342.
[13] VALVERDE-LÓPEZ F, MATAS-COBOS A M, ALEGRÍA-MOTTE C, et al. BISAP, RANSON, lactate and others biomarkers in prediction of severe acute pancreatitis in a European cohort[J].J Gastroenterol Heptol,2017, 32(9):1649-1656.
2021, Vol. 38 
