Abstract 【Objective】To investigate the drainage effect of single thoracic drainage tube combined with negative pressure drainage tube after single port thoracoscopic lung cancer radical operation. 【Methods】A total of 80 patients with non-small cell lung cancer who underwent SP-VATS radical resection from July 2015 to October 2019 were selected and randomly divided into observation group (single drainage combined with negative pressure drainage tube) and control group (conventional single drainage tube), 40 cases in each group. The postoperative drainage volume, hospital stay, catheter time and infection were recorded and compared between the two groups. The levels of serum C-reactive protein (CRP), tumor necrosis factor -α(TNF-α) and interleukin-8 (IL-8) were compared between the two groups.【Results】The postoperative drainage volume, hospital stay and tube time of the observation group were lower than those of the control group, and the postoperative wound infection rate of the observation group was lower than that of the control group, the differences were statistically significant ( P <0.05). The incidence of postoperative complications and the use rate of opioid analgesics in the observation group were lower than those in the control group ( P <0.05).The levels of serum CRP, TNF-α and IL-8 in the two groups 5d after operation were lower than those in the control group on postoperative 1day ( P <0.05).【Conclusion】The drainage effect of single thoracic drainage tube combined with negative pressure drainage after SP-VATS lung cancer radical operation is more significant than that of conventional use of thoracic drainage tube, which is conducive to reducing the inflammatory reaction, shortening the length of hospital stay, and has great significance for the prognosis of patients.
WANG Zhen-hua,ZHANG Li-guo,GUO Xi-xi. Analysis of the Effect of Single Hole Thoracoscopic Drainage Combined with Negative Pressure Drainage in the Treatment of Lung Cancer[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(3): 365-367.