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Analysis of Long-term Survival Status of Patients with Small Hepatocellular carcinoma Treated by Minimally Invasive Surgery |
WU Zhen-yang, MA Ben, WANG Da-wei |
Department of Hepatobiliary Surgery ,the Chaoyang Second Hospital ,Chaoyang, Liaoning 122000 |
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Abstract Objective To study the long term survival of patients with small hepatocellular carcinoma after minimally invasive surgery.Methods The clinical data of 115 patients with small hepatocellular carcinoma in our hospital were analyzed retrospectively, of which 43 cases were treated by laparotomy (open group) and 72 cases of minimally invasive surgery (minimally invasive group). The post-operative recovery of the two groups was observed, and the post-tumor recurrence and the long-term survival rate were observed.Results The incidence of complications in the minimally invasive group 5.56%(4/72)was significantly lower than that in the open group 16.28% (7/43). The difference was statistically significant (χ2=4.693,P=0.016<0.05), and the incidence of complications in the minimally invasive group was significantly lower than that in the open group (P<0.05). The hospitalization time in minimally invasive group was shorter than that in open group (P<0.05). There was no significant difference in the disease-free survival rate and the overall survival rate between the two groups at 1 year, 3 years and 5 years after operation by Kaplan-Meier plot and Log-rank method during follow-up (P>0.05), and there was no significant difference between the two groups (P>0.05). Conclusion The incidence of complications after minimally invasive surgery for small hepatocellular carcinoma is lower than that of open surgery, and the tumor-free survival rate and overall survival rate within 5 years are consistent with that of open operation. Minimally invasive surgery is a safe and effective method for the treatment of small hepatocellular carcinoma.
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Received: 17 September 2018
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