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| Correlation between Body Fat Distribution and Blood Lipid Metabolism in Patients with Coronary Heart Disease |
| JIAO Si-yu, CUI Yu-jie, JI Mei-jing, et al |
| The First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province,066000,China |
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Abstract 【Objective】To explore the correlation between body fat distribution and blood lipid metabolism in patients with coronary heart disease. 【Methods】A total of 70 coronary heart disease patients (the observation group) and 80 healthy volunteers ( the control group ) from June 2015 to June 2017 were enrolled in this study. Body fat composition and bone mineral density (BMD) were measured by dual-energy X-ray absorptiometry (DEXA). The levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and uric acid (UA) were compared between the two groups. The correlation between body fat distribution and lipid metabolism was analyzed in the coronary heart disease group. 【Results】There was no significant difference in age and BMI between the observation group and the control group (P>0.05). The levels of serum TG, TC, LDL-C and UA in the observation group were significantly higher than those in the control group (P<0.05), but the serum HDL-C levels were not significantly different (P>0.05). There was no significant difference in height and body weight between the observation group and the control group (P>0.05). The waist circumference, SBP and DBP in the observation group were significantly higher than the control group (P<0.05). The fat mass of the observation group was significantly higher than that of the control group, while the muscle mass, BMC and BMD were significantly lower than those of the control group (P<0.05). BMD and BMC were positively correlated with overall muscle mass, total fat mass, TG, TC and LDL-C (P<0.05).【Conclusion】Coronary heart disease has significant regression with fat mass, muscle mass, BMC and BMD, suggesting that body composition distribution and dyslipidemia play an important role in the occurrence and development of coronary heart disease.
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Received: 29 October 2018
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2018, Vol. 35 
