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| Efficacy of Qingyi Decoction Combined with Ulinastatin and Somatostatin in the Treatment of Acute Pancreatitis |
| FU Guifang1, QIU Yazhan2 |
1. Xinji Subdistrict Community Health Service Center of Xinxian, Xinyang Henan 465500;
2. Xinxian People's Hospital, Xinyang Henan 465550 |
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Abstract 【Objective】 To investigate the clinical efficacy of Qingyi Decoction combined with ulinastatin and somatostatin for patients with acute pancreatitis. 【Methods】 A total of 76 patients with acute pancreatitis admitted to Xinxian People's Hospital from July 2022 to July 2024 were enrolled and divided into observation group and control group by random number table method, with 38 cases in each group. The control group received combined treatment of ulinastatin and somatostatin; on the basis of the control group, the observation group was additionally given Qingyi Decoction. Traditional Chinese medicine (TCM) symptom scores and laboratory indicators including C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6), gastric inhibitory polypeptide (GIP), vasoactive intestinal peptide (VIP), lipase and amylase, as well as overall clinical efficacy were compared between the two groups before and after treatment. 【Results】 After treatment, the scores of TCM symptom scores in both groups were lower than those before treatment, and the observation group had lower scores than the control group (P<0.05). The serum levels of CRP, PCT, IL-6, amylase, lipase, GIP and VIP in both groups decreased after treatment, with significantly lower levels in the observation group compared with the control group (P<0.05). The total clinical effective rate of the observation group was higher than that of the control group (P<0.05). 【Conclusions】 Qingyi Decoction combined with ulinastatin and somatostatin can significantly relieve clinical symptoms, improve pancreatic function indicators and suppress inflammatory response in patients with acute pancreatitis, with superior therapeutic effect to single western medicine regimen.
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Received: 03 March 2026
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2026, Vol. 43 
