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Risk Factors of Multiple Cerebral Infarction Complicated with Pneumonia in the Elderly |
WANG Le, WANG Liu-yi, SHI Qiang |
Department of Neurologic Medicine, Affiliated Hospital of Yan'an University,Shaanxi 716000 |
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Abstract 【Objective】 To investigate the risk factors with multiple cerebral infarction complicated with pneumonia in the elderly patients.【Methods】 Forty-five elderly patients with multiple cerebral infarction complicated with pneumonia were enrolled in our hospital as the observation group, and 45 elderly patients with multiple cerebral infarction without pneumonia were selected as the control group. The basic clinical data, inflammation index, coagulation function and platelet parameters of the two groups were observed, and the related factors of multiple cerebral infarction complicated with pneumonia were analyzed. 【Results】 The age, number of infarctions, proportion of history of lung disease, and NIHSS scores in the observation group were higher than those in the control group (P<0.05). The levels of HS-CRP, IL-18,procalcitonin and SSA in the observation group were significantly higher than those in the control group (P<0.05). There was no significant difference in serum lipid levels between the two groups (P>0.05). The PDW (platelet distribution width) of the observation group was higher than that of the control group, while PCT and PLT were lower than those of the control group (P<0.05). There was no significant difference in coagulation function between the two groups (P>0.05). Multivariate analysis showed that platelet parameters, inflammatory markers, advanced age, and NIHSS scores were associated with pneumonia in the elderly patients with multiple cerebral infarction (P<0.05). 【Conclusion】 The elderly patients with multiple cerebral infarction complicated with pneumonia who are in aged, severe neurological deficits, high level of inflammatory response and platelet abnormalities need to be paid special attention clinically.
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Received: 27 October 2020
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